Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA6 | P23280 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | ESRRG | P62508 | 1/20 | 0.47 |
| ▸ | FAAH | O00519 | 1/20 | 0.47 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.46 |
| ▸ | CTSG | P08311 | 1/20 | 0.46 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.46 |
| ▸ | CMA1 | P23946 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24871620 | 1.00 | KDM4E (0.59) | KDM4EALDH1A1EGLN2KMT2AMEN1 | |
| SCHEMBL3655101 | 0.90 | KDM4E (0.59) | KDM4EALDH1A1EGLN2KMT2AMEN1 | |
| SCHEMBL161026 | 0.81 | KDM4E (0.65) | KDM4EALDH1A1EGLN2KMT2AMEN1 | |
| SCHEMBL23484191 | 0.80 | KDM4E (0.69) | KDM4EALDH1A1EGLN2KMT2AMEN1 | |
| SCHEMBL24871621 | 0.79 | ESRRG (0.55) | ALDH1A1KMT2AMEN1RAB9AGAA | |
| SCHEMBL27113108 | 0.78 | PTPRC (0.59) | KDM4EALDH1A1EGLN2KMT2AMEN1 | |
| SCHEMBL24871869 | 0.78 | HDAC6 (0.55) | KDM4EGAACA12CA1CA2 | |
| SCHEMBL30079776 | 0.78 | HDAC6 (0.55) | KDM4EGAACA12CA1CA2 | |
| SCHEMBL163436 | 0.78 | L3MBTL1 (0.71) | KDM4EALDH1A1EGLN2KMT2AMEN1 | |
| SCHEMBL159047 | 0.77 | KDM4E (0.61) | KDM4EALDH1A1EGLN2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4366717-A1 | BROAD-SPECTRUM ANTIVIRAL DRUGS | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) | 2024-05-15 | — | — | EP | disclosed |
| WO-2023281063-A1 | BROAD-SPECTRUM ANTIVIRAL DRUGS | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) | 2023-01-12 | — | — | WO | disclosed |