Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 1/20 | 0.52 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.45 |
| ▸ | OGA | O60502 | 1/20 | 0.44 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KIF18A | Q8NI77 | 2/20 | 0.41 |
| ▸ | NAPEPLD | Q6IQ20 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30080383 | 0.87 | CRBN (0.55) | CRBNHRH3OGAIRAK4CYP2D6 | |
| SCHEMBL1811182 | 0.86 | CYP1A2 (0.55) | CRBNHSD17B10ALDH1A1KIF18ANAPEPLD | |
| SCHEMBL1813506 | 0.83 | KDM4E (0.46) | CRBNIRAK4CYP2D6HSD17B10CYP3A4 | |
| SCHEMBL27233932 | 0.82 | KCNQ3 (0.39) | CRBNCYP2D6HSD17B10CYP3A4ALDH1A1 | |
| SCHEMBL31661791 | 0.81 | CRBN (0.54) | CRBNHRH3OGAIRAK4CYP2D6 | |
| SCHEMBL22849533 | 0.80 | IRAK4 (0.53) | CRBNHRH3OGAIRAK4ALDH1A1 | |
| SCHEMBL31078811 | 0.80 | IRAK4 (0.53) | CRBNHRH3OGAIRAK4ALDH1A1 | |
| SCHEMBL20745105 | 0.79 | CRBN (0.54) | CRBNCYP2D6HSD17B10CYP3A4ALDH1A1 | |
| SCHEMBL14879861 | 0.77 | HRH3 (0.58) | CRBNHRH3OGAIRAK4CYP3A4 | |
| SCHEMBL25160920 | 0.77 | SMO (0.39) | CYP2D6HSD17B10CYP3A4ALDH1A1KCNQ3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112996783-B | 2-aminopyrimidine derivatives, preparation method and application thereof in medicines | 江苏恒瑞医药股份有限公司 | 2022-11-18 | — | — | CN | disclosed |