Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 1/20 | 0.54 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.47 |
| ▸ | OGA | O60502 | 1/20 | 0.46 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | JAK1 | P23458 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30080407 | 0.81 | CRBN (0.52) | CRBNHRH3OGAIRAK4MEN1 | |
| SCHEMBL31661656 | 0.81 | CRBN (0.36) | CRBN | |
| SCHEMBL14879861 | 0.80 | HRH3 (0.58) | CRBNHRH3OGAIRAK4MEN1 | |
| SCHEMBL31661595 | 0.80 | CRBN (0.35) | CRBNMEN1KMT2AALDH1A1 | |
| SCHEMBL20548134 | 0.78 | HSD11B1 (0.59) | CRBNHRH3OGAIRAK4MEN1 | |
| SCHEMBL20000452 | 0.78 | PRKCQ (0.61) | CRBNHRH3OGAIRAK4MEN1 | |
| SCHEMBL31661756 | 0.77 | MAP3K12 (0.37) | CRBNOGAMEN1KMT2AALDH1A1 | |
| SCHEMBL3173613 | 0.77 | OGA (0.56) | CRBNHRH3OGAIRAK4MEN1 | |
| SCHEMBL22849533 | 0.76 | IRAK4 (0.53) | CRBNHRH3OGAIRAK4MAPT | |
| SCHEMBL31078811 | 0.76 | IRAK4 (0.53) | CRBNHRH3OGAIRAK4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025151403-A1 | 6-MEMBERED TRPML1 AGONISTS AND USES THEREOF | LIBRA THERAPEUTICS, INC. (US) | 2025-07-17 | — | — | WO | disclosed |