Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3013894 | 0.92 | — | — | |
| Hydrochloric Acid SCHEMBL3005477 | 0.91 | — | — | |
| Hydrochloric Acid SCHEMBL3015842 | 0.87 | — | — | |
| Hydrochloric Acid SCHEMBL2996520 | 0.86 | — | — | |
| Hydrochloric Acid SCHEMBL3000473 | 0.86 | — | — | |
| Hydrochloric Acid SCHEMBL3012393 | 0.85 | — | — | |
| Hydrochloric Acid SCHEMBL2996005 | 0.85 | — | — | |
| Hydrochloric Acid SCHEMBL3015752 | 0.85 | — | — | |
| Hydrochloric Acid SCHEMBL3000746 | 0.84 | — | — | |
| Hydrochloric Acid SCHEMBL3011402 | 0.84 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1838664-B1 | MANUFACTURE PROCESS OF N-SUBSTITUTED SALICYLAMIDES | NOVARTIS AG (CH) | 2015-07-15 | — | — | EP | disclosed |
| US-8461385-B2 | Manufacture process of organic compounds | NOVARTIS AG (CH) | 2013-06-11 | — | — | US | disclosed |
| US-20100190941-A1 | TRANSITION METAL COMPOUND, CATALYST FOR OLEFIN POLYMERIZATION, AND PROCESS FOR PRODUCING OLEFIN POLYMER | MITSUI CHEMICALS, INC. | 2010-07-29 | — | — | US | disclosed |
| US-20090253811-A1 | MANUFACTURE PROCESS OF ORGANIC COMPOUNDS | NOVARTIS AG (CH) | 2009-10-08 | — | — | US | disclosed |
| EP-1900744-A1 | TRANSITION METAL COMPOUND, OLEFIN POLYMERIZATION CATALYST, AND PROCESS FOR PRODUCING OLEFIN POLYMER | Mitsui Chemicals, Inc. (JP) | 2008-03-19 | — | — | EP | disclosed |
| EP-1838664-A1 | MANUFACTURE PROCESS OF N-SUBSTITUTED SALICYLAMIDES | Novartis AG (CH) | 2007-10-03 | — | — | EP | disclosed |
| WO-2006063821-A1 | MANUFACTURE PROCESS OF N-SUBSTITUTED SALICYLAMIDES | NOVARTIS AG (CH) | 2006-06-22 | — | — | WO | disclosed |