SCHEMBL30082669

SCHEMBL30082669

N=C(N)NCCC[C@H](N)C(=O)N[C@@H](Cc1ccccc1)C(=O)NCC(N)=O

nearest known ligand 0.55

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ NPY4R P50391 12/20 0.55
▸ NPY1R P25929 7/20 0.55
▸ NPY2R P49146 5/20 0.55
▸ NPY5R Q15761 5/20 0.55
▸ OPRM1 P35372 3/20 0.46
▸ OPRD1 P41143 3/20 0.46
▸ MMP2 P08253 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30998029 1.00 NPY4R (0.55) NPY4RNPY1RNPY2RNPY5ROPRM1
SCHEMBL30464872 0.94 NPY4R (0.53) NPY4RNPY1RNPY2RNPY5R
SCHEMBL9419225 0.94 NPY4R (0.55) NPY4RNPY1RNPY2RNPY5ROPRM1
SCHEMBL9419221 0.94 NPY4R (0.55) NPY4RNPY1RNPY2RNPY5ROPRM1
SCHEMBL31074747 0.94 NPY4R (0.55) NPY4RNPY1RNPY2RNPY5ROPRM1
SCHEMBL29419494 0.92 NPY4R (0.56) NPY4RNPY1RNPY2RNPY5ROPRD1
SCHEMBL13449160 0.91 NPY4R (0.60) NPY4RNPY1RNPY2RNPY5R
SCHEMBL29419547 0.90 NPY4R (0.53) NPY4RNPY1RNPY2RNPY5R
SCHEMBL29797028 0.90 NPY4R (0.52) NPY4RNPY1RNPY2RNPY5ROPRM1
SCHEMBL3933285 0.89 NPY4R (0.64) NPY4RNPY1RNPY2RNPY5R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250129118-A1 MELANOCORTIN 1 RECEPTOR LIGANDS AND METHODS OF USE H LEE MOFFITT CANCER CT & RES (US) 2025-04-24 — — US claimed
US-20250129118-A1 MELANOCORTIN 1 RECEPTOR LIGANDS AND METHODS OF USE H LEE MOFFITT CANCER CT & RES (US) 2025-04-24 — — US disclosed
WO-2024153981-A1 A MEDICINAL PRODUCT FOR USE IN ADMINISTERING IN THE TREATMENT, CONTROL AND/OR PREVENTION OF PAIN PVP LABS PTE. LTD. (SG) 2024-07-25 — — WO disclosed
EP-4355376-A1 METHODS AND MATERIALS FOR COMBINING BIOLOGICS WITH MULTIPLE CHELATORS Mayo Foundation for Medical Education and Research (US) 2024-04-24 — — EP disclosed
US-20230190857-A1 PEPTIDE WITH AMIDATED CARBOXY TERMINUS HAVING MELANOGENESIS INHIBITORY ACTIVITY AND COMPOSITION COMPRISING SAME RUBY CROWN CO. LTD. (KR) 2023-06-22 — — US disclosed
WO-2022266499-A1 METHODS AND MATERIALS FOR COMBINING BIOLOGICS WITH MULTIPLE CHELATORS MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) 2022-12-22 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250129118-A1 MELANOCORTIN 1 RECEPTOR LIGANDS AND METHODS OF USE MC1R, MC3R, MC5R NPY4R 40/4885NPY1R 14/4885NPY2R 45/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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