Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 1/20 | 0.49 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.49 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.47 |
| ▸ | GBA1 | P04062 | 4/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.44 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | LATS1 | O95835 | 3/20 | 0.43 |
| ▸ | PDE5A | O76074 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | LATS2 | Q9NRM7 | 2/20 | 0.41 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30085423 | 0.91 | CLK4 (0.51) | DYRK1ACLK4GBA1PPARGKMT2A | |
| SCHEMBL30085696 | 0.84 | CLK4 (0.58) | DYRK1ACLK4GBA1KMT2AALDH1A1 | |
| SCHEMBL30085439 | 0.83 | MEN1 (0.49) | DYRK1ACLK4KMT2ALMNACYP3A4 | |
| SCHEMBL30085548 | 0.83 | CLK4 (0.60) | DYRK1ACLK4GBA1KMT2AALDH1A1 | |
| SCHEMBL30085657 | 0.82 | MEN1 (0.48) | DYRK1ACLK4KMT2ALMNACYP3A4 | |
| SCHEMBL30085676 | 0.82 | PDE5A (0.56) | DYRK1ACLK4GBA1PPARGKMT2A | |
| SCHEMBL30085386 | 0.81 | CFTR (0.49) | DYRK1ACLK4GBA1KMT2AALDH1A1 | |
| SCHEMBL30085426 | 0.81 | KCNA5 (0.60) | DYRK1ACLK4GBA1KMT2APDE5A | |
| SCHEMBL30085577 | 0.80 | MEN1 (0.47) | DYRK1ACLK4KMT2AALDH1A1LMNA | |
| SCHEMBL30085496 | 0.80 | IRAK4 (0.50) | DYRK1ACLK4GBA1PPARGKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115397818-A | Aminopyrimidine derivatives and their use as modulators of arene receptors | 东亚ST株式会社 | 2022-11-25 | — | — | CN | claimed |
| CN-115397818-A | Aminopyrimidine derivatives and their use as modulators of arene receptors | 东亚ST株式会社 | 2022-11-25 | — | — | CN | disclosed |