Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLK4 | Q9HAZ1 | 7/20 | 0.60 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.60 |
| ▸ | PDE5A | O76074 | 3/20 | 0.54 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.53 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.53 |
| ▸ | USP1 | O94782 | 6/20 | 0.49 |
| ▸ | WDR48 | Q8TAF3 | 6/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 6/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | USP2 | O75604 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | GBA1 | P04062 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30085696 | 0.92 | CLK4 (0.58) | CLK4DYRK1APDE5AUSP1WDR48 | |
| SCHEMBL30085423 | 0.85 | CLK4 (0.51) | CLK4DYRK1APDE5AUSP1WDR48 | |
| SCHEMBL30085426 | 0.84 | KCNA5 (0.60) | CLK4DYRK1APDE5AIRAK1IRAK4 | |
| SCHEMBL30085562 | 0.83 | DYRK1A (0.49) | CLK4DYRK1APDE5AIRAK1USP1 | |
| SCHEMBL30085676 | 0.81 | PDE5A (0.56) | CLK4DYRK1APDE5AIRAK1IRAK4 | |
| SCHEMBL30085439 | 0.78 | MEN1 (0.49) | CLK4DYRK1AIRAK1IRAK4CYP1A2 | |
| SCHEMBL30085662 | 0.77 | IRAK1 (0.55) | CLK4DYRK1APDE5AIRAK1IRAK4 | |
| SCHEMBL28895174 | 0.76 | CLK4 (0.64) | CLK4DYRK1APDE5AUSP1WDR48 | |
| SCHEMBL30085882 | 0.76 | CLK4 (0.64) | CLK4DYRK1APDE5AUSP1WDR48 | |
| SCHEMBL8042391 | 0.75 | PDE5A (0.63) | CLK4DYRK1APDE5ACYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115397818-A | Aminopyrimidine derivatives and their use as modulators of arene receptors | 东亚ST株式会社 | 2022-11-25 | — | — | CN | claimed |
| CN-115397818-A | Aminopyrimidine derivatives and their use as modulators of arene receptors | 东亚ST株式会社 | 2022-11-25 | — | — | CN | disclosed |