Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.78 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28584191 | 1.00 | SLC22A12 (0.78) | SLC22A12KDM4EATMCHRM1LMNA | |
| SCHEMBL28573470 | 0.92 | SLC22A12 (0.78) | SLC22A12KDM4EATMCHRM1LMNA | |
| SCHEMBL28589443 | 0.89 | SLC22A12 (0.78) | SLC22A12KDM4EPOLBALDH1A1SMN1; SMN2 | |
| SCHEMBL28573025 | 0.89 | SLC22A12 (0.78) | SLC22A12KDM4ECHRM1LMNATHRB | |
| SCHEMBL28914750 | 0.89 | SLC22A12 (0.78) | SLC22A12KDM4ECHRM1LMNAPOLB | |
| SCHEMBL30089337 | 0.89 | SLC22A12 (0.78) | SLC22A12KDM4ECHRM1LMNATHRB | |
| SCHEMBL28589808 | 0.88 | SLC22A12 (1.00) | SLC22A12KDM4ELMNARAB9ASMN1; SMN2 | |
| SCHEMBL30089245 | 0.88 | SLC22A12 (0.74) | SLC22A12KDM4ECHRM1LMNAHPGD | |
| SCHEMBL28581670 | 0.88 | SLC22A12 (0.74) | SLC22A12KDM4ECHRM1LMNAHPGD | |
| SCHEMBL28578369 | 0.86 | SLC22A12 (0.74) | SLC22A12KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113004187-B | Compound with function of inhibiting activity of organic anion transporter 1, preparation method and application | 沈阳药科大学 | 2022-09-20 | — | — | CN | disclosed |