Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.78 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | F10 | P00742 | 1/20 | 0.45 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 3/20 | 0.43 |
| ▸ | CNR1 | P21554 | 2/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28573025 | 1.00 | SLC22A12 (0.78) | SLC22A12KDM4ELMNAHTTSMN1; SMN2 | |
| SCHEMBL28914750 | 0.92 | SLC22A12 (0.78) | SLC22A12KDM4ELMNAHTTSMN1; SMN2 | |
| SCHEMBL30089239 | 0.89 | SLC22A12 (0.78) | SLC22A12KDM4ELMNASMN1; SMN2POLB | |
| SCHEMBL28914786 | 0.89 | SLC22A12 (0.78) | SLC22A12KDM4ELMNAHTTSMN1; SMN2 | |
| SCHEMBL28573470 | 0.89 | SLC22A12 (0.78) | SLC22A12KDM4ELMNAHTTSMN1; SMN2 | |
| SCHEMBL28584191 | 0.89 | SLC22A12 (0.78) | SLC22A12KDM4ELMNASMN1; SMN2POLB | |
| SCHEMBL28589808 | 0.88 | SLC22A12 (1.00) | SLC22A12KDM4ELMNAHTTSMN1; SMN2 | |
| SCHEMBL28573465 | 0.85 | SLC22A12 (0.76) | SLC22A12KDM4ELMNAHTTPOLB | |
| SCHEMBL28580613 | 0.85 | SLC22A12 (0.72) | SLC22A12KDM4ESMN1; SMN2MEN1KMT2A | |
| SCHEMBL28584451 | 0.82 | SLC22A12 (0.81) | SLC22A12KDM4ELMNACNR2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113004187-B | Compound with function of inhibiting activity of organic anion transporter 1, preparation method and application | 沈阳药科大学 | 2022-09-20 | — | — | CN | disclosed |