Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.42 |
| ▸ | CKS1B | P61024 | 2/20 | 0.41 |
| ▸ | SKP1 | P63208 | 2/20 | 0.41 |
| ▸ | SKP2 | Q13309 | 2/20 | 0.41 |
| ▸ | MET | P08581 | 1/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.38 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.38 |
| ▸ | HTR3B | O95264 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | THPO | P40225 | 1/20 | 0.38 |
| ▸ | HTR3A | P46098 | 1/20 | 0.38 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30021359 | 0.95 | MAP4K4 (0.52) | MAP4K4ALDH1A1LMNAMAPTKCNH2 | |
| SCHEMBL23612102 | 0.95 | MAP4K4 (0.52) | MAP4K4ALDH1A1LMNAMAPTKCNH2 | |
| SCHEMBL30089468 | 0.88 | MAP4K4 (0.48) | MAP4K4ALDH1A1LMNAMAPTKCNH2 | |
| SCHEMBL23612106 | 0.88 | MAP4K4 (0.48) | MAP4K4ALDH1A1LMNAMAPTKCNH2 | |
| SCHEMBL23612021 | 0.84 | ALDH1A1 (0.50) | ALDH1A1LMNAMAPTHTR3EHTR3B | |
| Trifluoroacetic Acid SCHEMBL29727817 | 0.81 | ALDH1A1 (0.44) | ALDH1A1LMNAMAPTHTR3EHTR3B | |
| Trifluoroacetic Acid SCHEMBL29727819 | 0.81 | ALDH1A1 (0.44) | ALDH1A1LMNAMAPTHTR3EHTR3B | |
| SCHEMBL23625711 | 0.79 | MAP4K4 (0.61) | MAP4K4ALDH1A1LMNAMAPTKCNH2 | |
| SCHEMBL29727809 | 0.79 | MAP4K4 (0.61) | MAP4K4ALDH1A1LMNAMAPTKCNH2 | |
| SCHEMBL3174381 | 0.77 | MAPT (0.57) | MAP4K4ALDH1A1LMNAMAPTKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4085061-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY | IFM Due, Inc. (US) | 2022-11-09 | — | — | EP | disclosed |