Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.77 |
| ▸ | HPGD | P15428 | 5/20 | 0.77 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.77 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.58 |
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.52 |
| ▸ | CASP3 | P42574 | 1/20 | 0.52 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.52 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 3/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23412452 | 1.00 | KDM4E (0.77) | KDM4EHPGDALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL25061002 | 0.91 | HPGD (0.76) | KDM4EHPGDALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL30092936 | 0.90 | HPGD (0.71) | KDM4EHPGDALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL23412448 | 0.90 | HPGD (0.71) | KDM4EHPGDALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL29845739 | 0.89 | HPGD (0.70) | KDM4EHPGDALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL23413032 | 0.89 | HPGD (0.70) | KDM4EHPGDALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL30093114 | 0.85 | HPGD (0.68) | KDM4EHPGDALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL23413171 | 0.85 | HPGD (0.68) | KDM4EHPGDALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL23412447 | 0.85 | ALDH1A1 (0.73) | KDM4EHPGDALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL29846067 | 0.85 | ALDH1A1 (0.73) | KDM4EHPGDALDH1A1SMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115397806-A | Aryl and heteroaryl compounds and their therapeutic use in conditions associated with altered activity of galactocerebrosidase | 增益治疗股份有限公司 | 2022-11-25 | — | — | CN | disclosed |