Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.64 |
| ▸ | TSHR | P16473 | 2/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.64 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.64 |
| ▸ | POLB | P06746 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | LIN28A | Q9H9Z2 | 1/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | LTA4H | P09960 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3600311 | 0.94 | KDM4E (0.58) | KDM4ETSHRTDP1NPSR1POLB | |
| SCHEMBL12195603 | 0.93 | NPSR1 (0.75) | KDM4ETSHRTDP1NPSR1POLB | |
| SCHEMBL2280318 | 0.93 | KCNA5 (0.59) | KDM4ETSHRTDP1NPSR1POLB | |
| SCHEMBL804182 | 0.92 | TDP1 (0.63) | KDM4ETSHRTDP1NPSR1POLB | |
| Hydrochloric Acid SCHEMBL28308406 | 0.90 | TDP1 (0.61) | KDM4ETSHRTDP1NPSR1POLB | |
| SCHEMBL16523576 | 0.89 | TSHR (0.56) | KDM4ETSHRTDP1NPSR1POLB | |
| SCHEMBL27917498 | 0.89 | KDM4E (0.57) | KDM4ETSHRTDP1NPSR1POLB | |
| SCHEMBL29951011 | 0.87 | KDM4E (0.52) | KDM4ETSHRTDP1NPSR1POLB | |
| SCHEMBL27917501 | 0.86 | KDM4E (0.51) | KDM4ETSHRTDP1NPSR1POLB | |
| SCHEMBL14571205 | 0.85 | KDM4E (0.50) | KDM4ETSHRTDP1NPSR1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11517565-B2 | Bis-amines, compositions, and uses related to CXCR4 inhibition | EMORY UNIVERSITY (US) | 2022-12-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11517565-B2 | Bis-amines, compositions, and uses related to CXCR4 inhibition | CXCR4, CXCL12, CXCR2 | KDM4E 2201/4885TSHR 1634/4885TDP1 2025/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.