SCHEMBL804182

SCHEMBL804182

CN(Cc1ccccn1)Cc1ccccn1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 3/20 0.63
MAPT P10636 2/20 0.63
SMN1; SMN2 Q16637 1/20 0.63
LIN28A Q9H9Z2 1/20 0.63
KDM4E B2RXH2 2/20 0.53
TSHR P16473 2/20 0.53
NPSR1 Q6W5P4 1/20 0.53
POLB P06746 1/20 0.53
ALDH1A1 P00352 2/20 0.52
KCNA5 P22460 1/20 0.52
KMT2A Q03164 2/20 0.50
CYP2D6 P10635 2/20 0.49
CYP2C9 P11712 2/20 0.49
CYP2C19 P33261 2/20 0.49
RECQL P46063 1/20 0.49
HRH3 Q9Y5N1 1/20 0.48
HRH1 P35367 1/20 0.48
ATM Q13315 1/20 0.47
MAOA P21397 1/20 0.47
MAOB P27338 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL28308406 0.98 TDP1 (0.61) TDP1MAPTSMN1; SMN2LIN28AKDM4E
SCHEMBL18301478 0.92 TDP1 (0.55) TDP1MAPTSMN1; SMN2LIN28AKDM4E
SCHEMBL30093166 0.92 KDM4E (0.64) TDP1MAPTSMN1; SMN2LIN28AKDM4E
SCHEMBL996544 0.91 TDP1 (0.64) TDP1MAPTSMN1; SMN2LIN28AKDM4E
SCHEMBL3600311 0.90 KDM4E (0.58) TDP1MAPTSMN1; SMN2LIN28AKDM4E
SCHEMBL2323126 0.90 TDP1 (0.57) TDP1MAPTSMN1; SMN2LIN28AKDM4E
SCHEMBL6051881 0.88 TDP1 (0.60) TDP1MAPTSMN1; SMN2LIN28AKDM4E
SCHEMBL12245197 0.88 TDP1 (0.55) TDP1MAPTSMN1; SMN2LIN28AKDM4E
SCHEMBL22928656 0.87 TDP1 (0.59) TDP1MAPTSMN1; SMN2LIN28AKDM4E
SCHEMBL210394 0.86 TDP1 (0.63) TDP1MAPTSMN1; SMN2LIN28AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 170 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1506277-A1 ENZYMATIC DETERGENT COMPOSITIONS UNILEVER N.V. (NL) 2005-02-16 EP claimed
WO-2003097780-A1 ENZYMATIC DETERGENT COMPOSITIONS UNILEVER N.V. (NL) 2003-11-27 WO claimed
EP-1341893-A1 ENZYMATIC DETERGENT COMPOSITIONS UNILEVER N.V. (NL) 2003-09-10 EP claimed
WO-2002048307-A1 ENZYMATIC DETERGENT COMPOSITIONS UNILEVER N.V. (NL) 2002-06-20 WO claimed
CN-1351646-A Composition and method for bleaching a substrate UNILEVER PLC (NL) 2002-05-29 CN claimed
JP-9328494-A None JP disclosed
US-12460038-B2 Polymers and the use thereof for detecting ion fluxes Universite de Bordeaux (FR) 2025-11-04 US disclosed
EP-4406609-A2 METHOD FOR PRODUCING OPTICALLY ACTIVE COMPOUND Day One Biopharmaceuticals, Inc. (US) 2024-07-31 EP disclosed
US-11851410-B2 Sensors for detection of negatively charged phosphate-containing membranes and membrane components THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO (CA) 2023-12-26 US disclosed
US-20230243749-A1 METHOD OF DETECTING ENDOTOXIN, ENDOTOXIN DETECTION DEVICE, PURIFIED WATER PRODUCTION FACILITY, INJECTION WATER PRODUCTION FACILITY, METHOD OF PRODUCING PURIFIED WATER AND METHOD OF PRODUCING INJECTION WATER NOMURA MICRO SCIENCE CO., LTD. (JP) 2023-08-03 US disclosed
US-20230243749-A1 METHOD OF DETECTING ENDOTOXIN, ENDOTOXIN DETECTION DEVICE, PURIFIED WATER PRODUCTION FACILITY, INJECTION WATER PRODUCTION FACILITY, METHOD OF PRODUCING PURIFIED WATER AND METHOD OF PRODUCING INJECTION WATER NOMURA MICRO SCIENCE CO., LTD. (JP) 2023-08-03 US disclosed
US-11649222-B2 Compounds UNIVERSITETET I OSLO (NO) 2023-05-16 US disclosed
WO-2001016269-A1 METHOD OF BLEACHING STAINED FABRICS UNILEVER PLC (GB) 2001-03-08 WO disclosed
WO-2001016268-A1 METHOD OF PRETREATING AND BLEACHING STAINED FABRICS UNILEVER PLC (GB) 2001-03-08 WO disclosed
US-6008387-A MANGANESE COMPLEX CONTAINING A AMINO PYRIDINE LIGAND AS AN OXIDATION CATALYST FOR OXIDATION OF ORGANIC COMPOUNDS SUCH AS STYRENE HOECHST AKTIENGESELLSCHAFT (DE) 1999-12-28 US disclosed
US-6008387-A MANGANESE COMPLEX CONTAINING A AMINO PYRIDINE LIGAND AS AN OXIDATION CATALYST FOR OXIDATION OF ORGANIC COMPOUNDS SUCH AS STYRENE HOECHST AKTIENGESELLSCHAFT (DE) 1999-12-28 US disclosed
US-5789138-A Optical recording medium and method of producing the same RICOH COMPANY, LTD. (JP) 1998-08-04 US disclosed
JP-H09328494-A BIS-AND TRIS-(MU-OXO)-DIMANGANESE COMPLEXES, THEIR PRODUCTION AND THEIR USE HOECHST AG 1997-12-22 JP disclosed
EP-0782999-A1 Process for the oxidation of organic compounds in the presence of bis- and tris-(u-oxo)-dimanganese complex salts as a catalyst HOECHST AKTIENGESELLSCHAFT (DE) 1997-07-09 EP disclosed
EP-0782998-A1 Bis- and tris-(u-oxo)-dimanganese-complex salts, their preparation and their use HOECHST AKTIENGESELLSCHAFT (DE) 1997-07-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11851410-B2 Sensors for detection of negatively charged phosphate-containing membranes and membrane components PHOSPHO1, PTEN, INPPL1 TDP1 3575/4885MAPT 4429/4885SMN1; SMN2 4797/4885
US-12460038-B2 Polymers and the use thereof for detecting ion fluxes SLCO4C1, SLC9A2, SLCO2A1 TDP1 2826/4885MAPT 2396/4885SMN1; SMN2 3682/4885
US-11649222-B2 Compounds SLC30A6, SLC39A11, SLC39A3 TDP1 4608/4885MAPT 4706/4885SMN1; SMN2 3219/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.