Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 5/20 | 0.69 |
| ▸ | EPHA2 | P29317 | 3/20 | 0.69 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.69 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.69 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.69 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.69 |
| ▸ | LMNA | P02545 | 2/20 | 0.69 |
| ▸ | EFNA1 | P20827 | 1/20 | 0.69 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.69 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.69 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.69 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.69 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.69 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.69 |
| ▸ | MEN1 | O00255 | 1/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.69 |
| ▸ | RORC | P51449 | 1/20 | 0.56 |
| ▸ | CASP7 | P55210 | 3/20 | 0.53 |
| ▸ | TP53 | P04637 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31456225 | 0.90 | GPBAR1 (0.66) | GPBAR1EPHA2HSD17B10TDP1AKR1B10 | |
| SCHEMBL28036815 | 0.90 | GPBAR1 (0.66) | GPBAR1EPHA2HSD17B10TDP1AKR1B10 | |
| SCHEMBL11526749 | 0.88 | GPBAR1 (0.70) | GPBAR1EPHA2HSD17B10TDP1AKR1B10 | |
| SCHEMBL5501825 | 0.87 | GPBAR1 (0.68) | GPBAR1EPHA2HSD17B10TDP1AKR1B10 | |
| SCHEMBL15785703 | 0.86 | GPBAR1 (0.72) | GPBAR1EPHA2HSD17B10TDP1AKR1B10 | |
| SCHEMBL13139175 | 0.86 | GPBAR1 (0.72) | GPBAR1EPHA2HSD17B10TDP1AKR1B10 | |
| SCHEMBL7701966 | 0.86 | GPBAR1 (0.69) | GPBAR1EPHA2HSD17B10TDP1AKR1B10 | |
| SCHEMBL22404559 | 0.86 | GPBAR1 (0.72) | GPBAR1EPHA2HSD17B10TDP1AKR1B10 | |
| SCHEMBL7149599 | 0.86 | GPBAR1 (0.72) | GPBAR1EPHA2HSD17B10TDP1AKR1B10 | |
| SCHEMBL27625002 | 0.86 | GPBAR1 (0.72) | GPBAR1EPHA2HSD17B10TDP1AKR1B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111320664-B | Preparation method of 24-cholenenoic acid ethyl ester | 上海医药工业研究院 | 2023-01-24 | — | — | CN | disclosed |
| CN-111320663-B | Preparation method of 24-cholenenoic acid ethyl ester intermediate | 上海医药工业研究院 | 2023-01-24 | — | — | CN | disclosed |