SCHEMBL3009502

SCHEMBL3009502

NCCC(Oc1ccccc1)C(=O)O

nearest known ligand 0.56

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PPARG P37231 20/20 0.56
PPARA Q07869 18/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7890153 0.87 PPARG (0.45) PPARGPPARA
SCHEMBL4170587 0.85 PPARG (0.57) PPARGPPARA
SCHEMBL940490 0.83 PPARG (0.58) PPARGPPARA
SCHEMBL8935946 0.81 PPARG (0.73) PPARGPPARA
SCHEMBL5508320 0.81 PPARG (0.73) PPARGPPARA
SCHEMBL5509034 0.81 PPARG (0.56) PPARGPPARA
SCHEMBL28417484 0.80 PPARG (0.61) PPARGPPARA
SCHEMBL11516826 0.80 PPARG (0.79) PPARGPPARA
SCHEMBL5523874 0.79 PPARG (0.56) PPARGPPARA
SCHEMBL20592935 0.79 PPARG (0.54) PPARGPPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1002791-B1 AMINOETHYLPHENOXYACETIC ACID DERIVATIVES AND DRUGS FOR PAIN REMISSION AND CALCULI REMOVAL PROMOTION IN URINARY LITHIASIS KISSEI PHARMACEUTICAL (JP) 2004-10-20 EP claimed
CN-1137877-C Aminoethylphenoxyacetic acid derivatives and drugs for relieving pain of urolithiasis and promoting urinary calculus removal ����ҩƷ��ҵ��ʽ���� 2004-02-11 CN claimed
US-6399660-B1 AMINOETHYLPHENOXYACETIC ACID COMPOUND KISSEI PHARMACEUTICAL CO., LTD. (JP) 2002-06-04 US claimed
CN-1265091-A Aminoethylphanoxyacetic acid derivatives and drugs for pain remission and calculi removal promotion in urinary lithasis KISSEI PHARMACEUTICAL (JP) 2000-08-30 CN claimed
EP-1002791-A1 AMINOETHYLPHENOXYACETIC ACID DERIVATIVES AND DRUGS FOR PAIN REMISSION AND CALCULI REMOVAL PROMOTION IN URINARY LITHIASIS Kissei Pharmaceutical Co., Ltd. (JP) 2000-05-24 EP claimed
US-20100197788-A9 Preventive or therapeutic agent for disease caused by decrease in lacrimal fluid KISSEI PHARMACEUTICAL CO., LTD. (JP) 2010-08-05 US disclosed
US-20080306160-A1 Preventive or therapeutic agent for disease caused by decrease in lacrimal fluid KISSEI PHARMACEUTICAL CO., LTD. (JP) 2008-12-11 US disclosed
EP-1938837-A1 PREVENTIVE OR THERAPEUTIC AGENT FOR DISEASE CAUSED BY DECREASE IN LACRIMAL FLUID Kissei Pharmaceutical Co., Ltd. (JP) 2008-07-02 EP disclosed
US-7196203-B2 Phenol derivatives and method of use thereof KISSEI PHARMACEUTICAL CO., LTD. (JP) 2007-03-27 US disclosed
EP-1146035-B1 CRYSTAL POLYMORPHISM OF AMINOETHYLPHENOXYACETIC ACID DERIVATIVE KISSEI PHARMACEUTICAL (JP) 2005-11-16 EP disclosed
US-20050209486-A1 Phenol derivatives and method of use thereof KISSEI PHARMACEUTICAL CO., LTD. (JP) 2005-09-22 US disclosed
CN-1216855-C Polymorphs of aminoethylphenoxyacetic acid derivatives KISSEI PHARMACEUTICAL (JP) 2005-08-31 CN disclosed
EP-1146035-A1 CRYSTAL POLYMORPHISM OF AMINOETHYLPHENOXYACETIC ACID DERIVATIVE Kissei Pharmaceutical Co., Ltd. (JP) 2001-10-17 EP disclosed
EP-1002791-A4 AMINOETHYLPHENOXYACETIC ACID DERIVATIVES AND DRUGS FOR PAIN REMISSION AND CALCULI REMOVAL PROMOTION IN URINARY LITHIASIS KISSEI PHARMACEUTICAL (JP) 2001-09-12 EP disclosed
CN-1265091-A Aminoethylphanoxyacetic acid derivatives and drugs for pain remission and calculi removal promotion in urinary lithasis KISSEI PHARMACEUTICAL (JP) 2000-08-30 CN disclosed
CN-1265091-A Aminoethylphanoxyacetic acid derivatives and drugs for pain remission and calculi removal promotion in urinary lithasis KISSEI PHARMACEUTICAL (JP) 2000-08-30 CN disclosed
CN-1265091-A Aminoethylphanoxyacetic acid derivatives and drugs for pain remission and calculi removal promotion in urinary lithasis KISSEI PHARMACEUTICAL (JP) 2000-08-30 CN disclosed
EP-1002791-A1 AMINOETHYLPHENOXYACETIC ACID DERIVATIVES AND DRUGS FOR PAIN REMISSION AND CALCULI REMOVAL PROMOTION IN URINARY LITHIASIS Kissei Pharmaceutical Co., Ltd. (JP) 2000-05-24 EP disclosed
EP-1002791-A1 AMINOETHYLPHENOXYACETIC ACID DERIVATIVES AND DRUGS FOR PAIN REMISSION AND CALCULI REMOVAL PROMOTION IN URINARY LITHIASIS Kissei Pharmaceutical Co., Ltd. (JP) 2000-05-24 EP disclosed
WO-1999005090-A1 AMINOETHYLPHENOXYACETIC ACID DERIVATIVES AND DRUGS FOR PAIN REMISSION AND CALCULI REMOVAL PROMOTION IN URINARY LITHIASIS KISSEI PHARMACEUTICAL CO., LTD. (JP) 1999-02-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050209486-A1 Phenol derivatives and method of use thereof COMT, TYR, NQO1 PPARG 15/4885PPARA 34/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.