Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 20/20 | 0.73 |
| ▸ | PPARA | Q07869 | 18/20 | 0.73 |
| ▸ | PTGES | O14684 | 1/20 | 0.52 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5508320 | 1.00 | PPARG (0.73) | PPARGPPARAPTGESALOX5 | |
| SCHEMBL289442 | 0.89 | PPARG (0.64) | PPARGPPARAPTGESALOX5 | |
| SCHEMBL8935884 | 0.89 | PPARG (0.64) | PPARGPPARAPTGESALOX5 | |
| SCHEMBL557511 | 0.88 | CTRC (0.62) | PPARGPPARAPTGESALOX5 | |
| SCHEMBL22828775 | 0.86 | CTRC (0.64) | PPARGPPARAPTGESALOX5 | |
| SCHEMBL15903011 | 0.86 | CTRC (0.64) | PPARGPPARAPTGESALOX5 | |
| SCHEMBL6342298 | 0.86 | CTRC (0.64) | PPARGPPARAPTGESALOX5 | |
| SCHEMBL4002165 | 0.86 | CTRC (0.64) | PPARGPPARAPTGESALOX5 | |
| SCHEMBL11531304 | 0.86 | CTRC (0.64) | PPARGPPARAPTGESALOX5 | |
| SCHEMBL4001414 | 0.86 | CTRC (0.64) | PPARGPPARAPTGESALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5491167-A | INHIBITORS OF CHOLESTEROL BIOSYNTHESIS | SANKYO COMPANY, LIMITED (JP) | 1996-02-13 | — | — | US | disclosed |