Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAT2A | P31153 | 7/20 | 0.48 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.33 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.33 |
| ▸ | PTGES | O14684 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | CASP1 | P29466 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.30 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.30 |
| ▸ | GRM5 | P41594 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24809004 | 1.00 | MAT2A (0.48) | MAT2ACSNK2A2CSNK2BPTGESEGFR | |
| SCHEMBL24808669 | 0.89 | MAT2A (0.47) | MAT2A | |
| SCHEMBL29162211 | 0.88 | MAT2A (0.41) | MAT2APTGES | |
| SCHEMBL30095852 | 0.87 | MAT2A (0.41) | MAT2APTGESKDM4EMEN1CASP1 | |
| SCHEMBL24807042 | 0.87 | MAT2A (0.41) | MAT2APTGESKDM4EMEN1CASP1 | |
| SCHEMBL24807078 | 0.82 | MAT2A (0.50) | MAT2AMAP3K14KMT2AGRM4GRM5 | |
| SCHEMBL30095731 | 0.81 | MAT2A (0.53) | MAT2ACSNK2A2CSNK2BPTGESEGFR | |
| SCHEMBL24807303 | 0.81 | MAT2A (0.53) | MAT2ACSNK2A2CSNK2BPTGESEGFR | |
| SCHEMBL24809903 | 0.80 | MAT2A (0.47) | MAT2A | |
| SCHEMBL30095560 | 0.80 | MAT2A (0.47) | MAT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4359389-A1 | DIACYLGLYERCOL KINASE MODULATING COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2024-05-01 | — | — | EP | disclosed |
| WO-2022271677-A1 | DIACYLGLYERCOL KINASE MODULATING COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2022-12-29 | — | — | WO | disclosed |