Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE9A | O76083 | 13/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | PDE1C | Q14123 | 2/20 | 0.38 |
| ▸ | BCDIN3D | Q7Z5W3 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PDE2A | O00408 | 1/20 | 0.35 |
| ▸ | PLK4 | O00444 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29174761 | 1.00 | PDE9A (0.40) | PDE9AKDM4EPDE1CBCDIN3DKMT2A | |
| SCHEMBL22805419 | 0.83 | PDE2A (0.53) | BCDIN3DKMT2APDE2A | |
| SCHEMBL2357706 | 0.79 | KDM4E (0.43) | PDE9AKDM4EPDE1CKMT2APDE2A | |
| SCHEMBL30095729 | 0.78 | KDM4E (0.42) | PDE9AKDM4EPDE1CKMT2APDE2A | |
| SCHEMBL29175001 | 0.78 | KDM4E (0.42) | PDE9AKDM4EPDE1CKMT2APDE2A | |
| SCHEMBL24500179 | 0.76 | KDM4E (0.41) | PDE9AKDM4EPDE1CKMT2APDE2A | |
| SCHEMBL30095905 | 0.76 | KDM4E (0.44) | PDE9AKDM4EPDE1CKMT2APDE2A | |
| SCHEMBL30095889 | 0.76 | KDM4E (0.44) | PDE9AKDM4EPDE1CKMT2APDE2A | |
| SCHEMBL29174857 | 0.76 | KDM4E (0.44) | PDE9AKDM4EPDE1CKMT2APDE2A | |
| SCHEMBL29174869 | 0.76 | KDM4E (0.44) | PDE9AKDM4EPDE1CKMT2APDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4346806-A2 | IMIDAZOLE-CONTAINING INHIBITORS OF ALK2 KINASE | Biocryst Pharmaceuticals, Inc. (US) | 2024-04-10 | — | — | EP | disclosed |
| CN-117529315-A | Imidazole-containing ALK2 kinase inhibitors | 生物水晶制药公司 | 2024-02-06 | — | — | CN | disclosed |
| WO-2022251188-A2 | IMIDAZOLE-CONTAINING INHIBITORS OF ALK2 KINASE | BIOCRYST PHARMACEUTICALS, INC. (US) | 2022-12-01 | — | — | WO | disclosed |