Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | PDE1C | Q14123 | 2/20 | 0.40 |
| ▸ | PDE9A | O76083 | 11/20 | 0.40 |
| ▸ | CDK1 | P06493 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PDE2A | O00408 | 1/20 | 0.37 |
| ▸ | NT5E | P21589 | 2/20 | 0.35 |
| ▸ | PI4KA | P42356 | 1/20 | 0.34 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.34 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.34 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29399563 | 0.83 | CDK1 (0.44) | KDM4EPDE1CPDE9ACDK1KMT2A | |
| SCHEMBL21459294 | 0.83 | CDK1 (0.44) | KDM4EPDE1CPDE9ACDK1KMT2A | |
| SCHEMBL2357706 | 0.83 | KDM4E (0.43) | KDM4EPDE1CPDE9AKMT2APDE2A | |
| SCHEMBL24500614 | 0.81 | KDM4E (0.42) | KDM4EPDE1CPDE9AKMT2API4KA | |
| SCHEMBL30095729 | 0.81 | KDM4E (0.42) | KDM4EPDE1CPDE9AKMT2APDE2A | |
| SCHEMBL29175001 | 0.81 | KDM4E (0.42) | KDM4EPDE1CPDE9AKMT2APDE2A | |
| SCHEMBL30095905 | 0.80 | KDM4E (0.44) | KDM4EPDE1CPDE9AKMT2APDE2A | |
| SCHEMBL30095889 | 0.80 | KDM4E (0.44) | KDM4EPDE1CPDE9AKMT2APDE2A | |
| SCHEMBL29174857 | 0.80 | KDM4E (0.44) | KDM4EPDE1CPDE9AKMT2APDE2A | |
| SCHEMBL29174869 | 0.80 | KDM4E (0.44) | KDM4EPDE1CPDE9AKMT2APDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220177510-A1 | DERIVATIVES OF GYLCERO-MANNO-HEPTOSE ADP FOR USE IN MODULATING IMMUNE RESPONSE | SHANGHAI YAO YUAN BIOTECHNOLOGY CO LTD (CN) | 2022-06-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220177510-A1 | DERIVATIVES OF GYLCERO-MANNO-HEPTOSE ADP FOR USE IN MODULATING IMMUNE RESPONSE | GALK1, PHKA1, PGK1 | KDM4E 3561/4885PDE1C 1949/4885PDE9A 2061/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.