Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 5/20 | 0.54 |
| ▸ | RICTOR | Q6R327 | 3/20 | 0.54 |
| ▸ | RPTOR | Q8N122 | 3/20 | 0.54 |
| ▸ | MAPKAP1 | Q9BPZ7 | 3/20 | 0.54 |
| ▸ | MLST8 | Q9BVC4 | 3/20 | 0.54 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.34 |
| ▸ | ABL1 | P00519 | 2/20 | 0.34 |
| ▸ | EGFR | P00533 | 2/20 | 0.34 |
| ▸ | HCK | P08631 | 2/20 | 0.34 |
| ▸ | SRC | P12931 | 2/20 | 0.34 |
| ▸ | KDR | P35968 | 2/20 | 0.34 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.34 |
| ▸ | EPHB4 | P54760 | 2/20 | 0.34 |
| ▸ | PRKDC | P78527 | 2/20 | 0.34 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.34 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.34 |
| ▸ | AAK1 | Q2M2I8 | 15/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22494331 | 0.72 | MTOR (0.50) | MTORRICTORRPTORMAPKAP1MLST8 | |
| SCHEMBL30381902 | 0.72 | MTOR (0.50) | MTORRICTORRPTORMAPKAP1MLST8 | |
| SCHEMBL22494329 | 0.72 | MTOR (0.50) | MTORRICTORRPTORMAPKAP1MLST8 | |
| SCHEMBL22494262 | 0.70 | MTOR (1.00) | MTORRICTORRPTORMAPKAP1MLST8 | |
| SCHEMBL22494261 | 0.70 | MTOR (1.00) | MTORRICTORRPTORMAPKAP1MLST8 | |
| SCHEMBL30214463 | 0.70 | SRC (0.68) | MTORPIK3CAPIK3CDABL1EGFR | |
| SCHEMBL22494333 | 0.70 | MTOR (1.00) | MTORRICTORRPTORMAPKAP1MLST8 | |
| SCHEMBL22494330 | 0.70 | MTOR (1.00) | MTORRICTORRPTORMAPKAP1MLST8 | |
| SCHEMBL22494342 | 0.69 | MTOR (0.70) | MTORRICTORRPTORMAPKAP1MLST8 | |
| SCHEMBL22494344 | 0.69 | MTOR (0.70) | MTORRICTORRPTORMAPKAP1MLST8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4370517-A1 | SYNTHESIS OF CHIRAL SUBSTITUTED PYRAZOLOPYRIMIDINE COMPOUNDS | Galderma Holding SA (CH) | 2024-05-22 | — | — | EP | disclosed |
| WO-2023285926-A1 | SYNTHESIS OF CHIRAL SUBSTITUTED PYRAZOLOPYRIMIDINE COMPOUNDS | Galderma Holding SA (CH) | 2023-01-19 | — | — | WO | disclosed |