Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 3/20 | 0.50 |
| ▸ | RICTOR | Q6R327 | 3/20 | 0.50 |
| ▸ | RPTOR | Q8N122 | 3/20 | 0.50 |
| ▸ | MAPKAP1 | Q9BPZ7 | 3/20 | 0.50 |
| ▸ | MLST8 | Q9BVC4 | 3/20 | 0.50 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
| ▸ | CDK1 | P06493 | 1/20 | 0.32 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.32 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.32 |
| ▸ | CDK2 | P24941 | 1/20 | 0.32 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.32 |
| ▸ | DHFR | P00374 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22494329 | 1.00 | MTOR (0.50) | MTORRICTORRPTORMAPKAP1MLST8 | |
| SCHEMBL30381902 | 1.00 | MTOR (0.50) | MTORRICTORRPTORMAPKAP1MLST8 | |
| Oxalic Acid SCHEMBL30095943 | 0.92 | MTOR (0.45) | MTORRICTORRPTORMAPKAP1MLST8 | |
| Oxalic Acid SCHEMBL30095959 | 0.92 | MTOR (0.45) | MTORRICTORRPTORMAPKAP1MLST8 | |
| SCHEMBL30964192 | 0.81 | MTOR (0.35) | MTORRICTORRPTORMAPKAP1MLST8 | |
| SCHEMBL30414236 | 0.81 | MTOR (0.35) | MTORRICTORRPTORMAPKAP1MLST8 | |
| SCHEMBL4572205 | 0.73 | PIK3CD (0.36) | MTORPIK3CA | |
| SCHEMBL30096051 | 0.72 | MTOR (0.54) | MTORRICTORRPTORMAPKAP1MLST8 | |
| SCHEMBL30096023 | 0.69 | MTOR (0.41) | MTORRICTORRPTORMAPKAP1MLST8 | |
| SCHEMBL4572181 | 0.69 | PDE8B (0.39) | MTORPIK3CACDK1CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250042908-A1 | SALTS FOR MTOR COMPOUNDS | GALDERMA HOLDING S A (CH) | 2025-02-06 | — | — | US | disclosed |
| US-11731973-B2 | Substituted pyrazolo[3,4-d]pyrimidines as mTOR inhibitors | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2023-08-22 | — | — | US | disclosed |
| EP-3727389-B1 | COMPOUNDS AS MTOR INHIBITORS | GALDERMA RES & DEV (FR) | 2023-05-03 | — | — | EP | disclosed |
| CN-111918653-A | Novel MTOR inhibitor compounds | 盖尔德马研究及发展公司 | 2020-11-10 | — | — | CN | disclosed |
| EP-3727389-A1 | NOVEL MTOR INHIBITOR COMPOUNDS | Galderma Research & Development (FR) | 2020-10-28 | — | — | EP | disclosed |
| US-20200317679-A1 | NOVEL MTOR INHIBITOR COMPOUNDS | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2020-10-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200317679-A1 | NOVEL MTOR INHIBITOR COMPOUNDS | MTOR, RICTOR, RPTOR | MTOR 1/4885RICTOR 2/4885RPTOR 3/4885 |
| US-20250042908-A1 | SALTS FOR MTOR COMPOUNDS | MTOR, RICTOR, PIK3CA | MTOR 1/4885RICTOR 2/4885RPTOR 9/4885 |
| US-11731973-B2 | Substituted pyrazolo[3,4-d]pyrimidines as mTOR inhibitors | MTOR, RICTOR, RPTOR | MTOR 1/4885RICTOR 2/4885RPTOR 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.