Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 10/20 | 0.57 |
| ▸ | P2RX7 | Q99572 | 8/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30096069 | 0.77 | HDAC6 (0.60) | HDAC6P2RX7HDAC3HDAC1HDAC2 | |
| SCHEMBL30096079 | 0.77 | P2RX7 (0.58) | HDAC6P2RX7HDAC3HDAC1HDAC2 | |
| SCHEMBL30096078 | 0.76 | HDAC6 (0.58) | HDAC6P2RX7HDAC3HDAC1HDAC2 | |
| SCHEMBL30096076 | 0.76 | HDAC6 (0.61) | HDAC6P2RX7HDAC3HDAC1HDAC2 | |
| SCHEMBL3458610 | 0.74 | P2RX7 (0.68) | P2RX7 | |
| SCHEMBL30096075 | 0.74 | HDAC6 (0.61) | HDAC6P2RX7HDAC3HDAC1HDAC2 | |
| SCHEMBL7572019 | 0.72 | P2RX7 (0.62) | P2RX7 | |
| SCHEMBL20535205 | 0.72 | HDAC6 (1.00) | HDAC6P2RX7HDAC3HDAC1HDAC2 | |
| SCHEMBL20535185 | 0.72 | HDAC6 (1.00) | HDAC6P2RX7HDAC3HDAC1HDAC2 | |
| SCHEMBL20535184 | 0.71 | HDAC6 (1.00) | HDAC6P2RX7HDAC3HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115869428-A | HDAC6 inhibitors and imaging agents | 通用医疗公司 | 2023-03-31 | — | — | CN | disclosed |
| CN-110770206-B | HDAC6 inhibitors | 通用医疗公司 | 2022-11-25 | — | — | CN | disclosed |