Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ORAI1 | Q96D31 | 6/20 | 0.41 |
| ▸ | STIM1 | Q13586 | 4/20 | 0.41 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.39 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.39 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.36 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.35 |
| ▸ | RIPK3 | Q9Y572 | 1/20 | 0.35 |
| ▸ | PTGES | O14684 | 1/20 | 0.34 |
| ▸ | PDE5A | O76074 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.33 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.32 |
| ▸ | WEE1 | P30291 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15021833 | 1.00 | ORAI1 (0.41) | ORAI1STIM1FGFR2FGFR3TRPV3 | |
| SCHEMBL15751092 | 0.93 | ORAI1 (0.45) | ORAI1STIM1FGFR2FGFR3TRPV3 | |
| SCHEMBL15750816 | 0.88 | ORAI1 (0.43) | ORAI1STIM1FGFR2FGFR3PTGES | |
| SCHEMBL30096544 | 0.85 | STIM1 (0.38) | ORAI1STIM1FGFR2FGFR3TRPV3 | |
| SCHEMBL15021884 | 0.85 | STIM1 (0.38) | ORAI1STIM1FGFR2FGFR3TRPV3 | |
| SCHEMBL15021817 | 0.85 | TRPV3 (0.39) | ORAI1STIM1TRPV3RIPK2RIPK3 | |
| SCHEMBL15020867 | 0.84 | ORAI1 (0.55) | ORAI1STIM1FGFR2FGFR3PTGES | |
| SCHEMBL15021651 | 0.81 | CDK5 (0.43) | ORAI1STIM1FGFR2FGFR3TRPV3 | |
| SCHEMBL15751234 | 0.80 | ORAI1 (0.52) | ORAI1FGFR2FGFR3PTGESCHRNB2 | |
| SCHEMBL15021819 | 0.77 | TRPV3 (0.42) | ORAI1STIM1TRPV3PDE5AKDM5B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4465988-A1 | METHODS AND COMPOSITIONS FOR TREATING INFLAMMATION INJURY IN THE LUNGS | Calcimedica, Inc. (US) | 2024-11-27 | — | — | EP | disclosed |
| CN-118871110-A | Methods and compositions for treating inflammatory lesions of the lung | 钙医学公司 | 2024-10-29 | — | — | CN | disclosed |
| WO-2023141523-A1 | METHODS AND COMPOSITIONS FOR TREATING INFLAMMATION INJURY IN THE LUNGS | CALCIMEDICA, INC. (US) | 2023-07-27 | — | — | WO | disclosed |
| CN-115835878-A | Methods and compositions for treating acute lung injury and acute respiratory distress syndrome | 钙医学公司 | 2023-03-21 | — | — | CN | disclosed |
| EP-4121089-A1 | METHODS AND COMPOSITIONS FOR TREATING ACUTE LUNG INJURY AND ACUTE RESPIRATORY DISTRESS SYNDROME | Calcimedica, Inc. (US) | 2023-01-25 | — | — | EP | disclosed |