Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB8 | P28062 | 11/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | CRHBP | P24387 | 1/20 | 0.37 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.37 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.32 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23706120 | 1.00 | PSMB8 (0.46) | PSMB8ALDH1A1KDM4EHPGDCYP3A4 | |
| SCHEMBL8781343 | 0.85 | PSMB8 (0.46) | PSMB8ALDH1A1KDM4EHPGDCYP3A4 | |
| SCHEMBL19153837 | 0.78 | CMA1 (0.44) | ALDH1A1 | |
| SCHEMBL11110131 | 0.69 | PSMB8 (0.61) | PSMB8ALDH1A1KDM4EHPGDCYP3A4 | |
| SCHEMBL13740465 | 0.68 | PSMB8 (0.38) | PSMB8ALDH1A1KDM4EHPGDCYP3A4 | |
| SCHEMBL11478869 | 0.67 | ALDH1A1 (0.60) | PSMB8ALDH1A1KDM4EHPGDCYP3A4 | |
| SCHEMBL30443775 | 0.67 | ALDH1A1 (0.55) | PSMB8ALDH1A1KDM4EHPGDCYP3A4 | |
| SCHEMBL12041942 | 0.67 | ALDH1A1 (0.55) | PSMB8ALDH1A1KDM4EHPGDCYP3A4 | |
| SCHEMBL19039375 | 0.65 | UHRF1 (0.39) | ALDH1A1KDM4EHPGDCYP1A2MAPT | |
| SCHEMBL1001304 | 0.64 | ALDH1A1 (0.56) | PSMB8ALDH1A1KDM4EHPGDCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115297861-B | Compounds and uses thereof | 福宏治疗公司 | 2024-07-12 | — | — | CN | disclosed |
| EP-4096667-A1 | COMPOUNDS AND USES THEREOF | Foghorn Therapeutics Inc. (US) | 2022-12-07 | — | — | EP | disclosed |