Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 1/20 | 0.55 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 2/20 | 0.44 |
| ▸ | CLK1 | P49759 | 3/20 | 0.43 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.43 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | AHR | P35869 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 2/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.37 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.37 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.37 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.36 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL849441 | 1.00 | CYP2A6 (0.55) | CYP2A6GPR84FFAR1HTR2ACLK1 | |
| SCHEMBL28973447 | 0.80 | CYP2A6 (0.60) | CYP2A6GPR84FFAR1HTR2ACLK1 | |
| SCHEMBL31332574 | 0.75 | GPR84 (0.58) | GPR84FFAR1HTR2ASLC6A4HTR2C | |
| SCHEMBL17308781 | 0.75 | GPR84 (0.58) | GPR84FFAR1HTR2ASLC6A4HTR2C | |
| SCHEMBL15826665 | 0.75 | GPR84 (0.58) | GPR84FFAR1HTR2ASLC6A4HTR2C | |
| SCHEMBL3614670 | 0.75 | CYP2A6 (0.55) | CYP2A6GPR84FFAR1HTR2ACLK1 | |
| SCHEMBL31663257 | 0.75 | CYP2A6 (0.55) | CYP2A6GPR84FFAR1HTR2ACLK1 | |
| SCHEMBL13544712 | 0.75 | CYP2A6 (0.55) | CYP2A6GPR84FFAR1CLK1CDK5 | |
| SCHEMBL19400908 | 0.75 | CYP2A6 (0.55) | CYP2A6GPR84FFAR1HTR2ACLK1 | |
| SCHEMBL28879718 | 0.75 | CYP2A6 (0.59) | CYP2A6GPR84FFAR1CLK1CDK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120192307-A | Compounds targeting p53 mutations | 上海齐鲁制药研究中心有限公司 | 2025-06-24 | — | — | CN | disclosed |
| EP-4096667-A1 | COMPOUNDS AND USES THEREOF | Foghorn Therapeutics Inc. (US) | 2022-12-07 | — | — | EP | disclosed |