Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 4/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | THRA | P10827 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 2/20 | 0.36 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30405540 | 0.80 | PLAU (0.33) | CNR1GAA | |
| SCHEMBL30042583 | 0.80 | PLAU (0.33) | CNR1GAA | |
| SCHEMBL23705809 | 0.79 | PLAU (0.43) | TDP1ALDH1A1L3MBTL1THRATHRB | |
| SCHEMBL30042575 | 0.79 | PLAU (0.43) | TDP1ALDH1A1L3MBTL1THRATHRB | |
| SCHEMBL23705893 | 0.74 | MEN1 (0.36) | ALDH1A1NPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL30042623 | 0.74 | MEN1 (0.36) | ALDH1A1NPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL23243202 | 0.69 | HPGD (0.42) | ALDH1A1L3MBTL1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6252442 | 0.67 | ALDH1A1 (0.62) | TDP1ALDH1A1L3MBTL1ESR1THRB | |
| SCHEMBL21275447 | 0.66 | ALDH1A1 (0.56) | TDP1ALDH1A1L3MBTL1HPGD | |
| SCHEMBL29342260 | 0.66 | ALDH1A1 (0.53) | TDP1ALDH1A1L3MBTL1ESR1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4096667-A1 | COMPOUNDS AND USES THEREOF | Foghorn Therapeutics Inc. (US) | 2022-12-07 | — | — | EP | disclosed |