Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 known ✓ | P11229 | 1/20 | 0.34 |
| ▸ | CHRM3 known ✓ | P20309 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.35 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.35 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.35 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.35 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.35 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27922571 | 0.85 | SLC1A2 (0.44) | GRIK1SLC1A3SLC1A2SLC1A1GRIK2 | |
| SCHEMBL25515651 | 0.83 | GRIK1 (0.35) | ALDH1A1GRIK1SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL28997263 | 0.82 | GRIK1 (0.47) | GRIK1SLC1A2SLC1A1GRIK2NAAA | |
| SCHEMBL1289774 | 0.82 | GRIK1 (0.47) | GRIK1SLC1A2SLC1A1GRIK2NAAA | |
| SCHEMBL28997992 | 0.80 | GRIK1 (0.46) | GRIK1SLC1A2SLC1A1GRIK2NAAA | |
| SCHEMBL28997460 | 0.80 | GRIK1 (0.46) | GRIK1SLC1A2SLC1A1GRIK2NAAA | |
| SCHEMBL27963798 | 0.80 | GRIK1 (0.46) | GRIK1SLC1A2SLC1A1GRIK2NAAA | |
| SCHEMBL9480412 | 0.79 | SLC1A2 (0.39) | ALDH1A1GRIK1SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL9482413 | 0.79 | SLC1A2 (0.39) | ALDH1A1GRIK1SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL2633798 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022271969-A2 | PRODRUGS OF ACYL CARNITINES | ATAI Life Sciences AG (DE) | 2022-12-29 | — | — | WO | disclosed |