Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A2 | P43004 | 3/20 | 0.39 |
| ▸ | SLC1A1 | P43005 | 3/20 | 0.39 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.39 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.39 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28276532 | 0.93 | HDAC7 (0.35) | SLC1A2SLC1A1SLC1A3GRIK1GRIK2 | |
| SCHEMBL9482413 | 0.85 | SLC1A2 (0.39) | SLC1A2SLC1A1SLC1A3GRIK1GRIK2 | |
| SCHEMBL1033366 | 0.85 | ALDH1A1 (0.43) | SLC1A2SLC1A1SLC1A3GRIK1GRIK2 | |
| SCHEMBL4630307 | 0.84 | GRIK1 (0.48) | SLC1A2SLC1A1SLC1A3GRIK1GRIK2 | |
| Butane SCHEMBL1033068 | 0.83 | ALDH1A1 (0.41) | SLC1A2SLC1A1SLC1A3GRIK1GRIK2 | |
| SCHEMBL933721 | 0.83 | — | — | |
| SCHEMBL27703023 | 0.83 | — | — | |
| SCHEMBL5968376 | 0.82 | GRIK1 (0.50) | SLC1A2SLC1A1GRIK1GRIK2TP53 | |
| SCHEMBL1401796 | 0.82 | GRIK1 (0.50) | SLC1A2SLC1A1GRIK1GRIK2TP53 | |
| SCHEMBL27918872 | 0.82 | GRIK1 (0.50) | SLC1A2SLC1A1GRIK1GRIK2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104254535-A | SUBSTITUTED PYRAZOLO[1,5-A]PYRIDINES, THEIR PREPARATION AND USE AS MEDICAMENTS | ESTEVE LABOR DR | 2014-12-31 | — | — | CN | claimed |
| JP-5119186-A | — | — | None | — | — | JP | disclosed |
| CN-105461693-A | Crth2 antagonist compound and use thereof | GUANGDONG HEC PHARMACEUTICAL | 2016-04-06 | — | — | CN | disclosed |
| CN-104254535-A | SUBSTITUTED PYRAZOLO[1,5-A]PYRIDINES, THEIR PREPARATION AND USE AS MEDICAMENTS | ESTEVE LABOR DR | 2014-12-31 | — | — | CN | disclosed |
| JP-H05119186-A | METHOD FOR REGENERATING REPROCESSED ORGANIC SOLVENT | JAPAN ATOM ENERGY RES INST | 1993-05-18 | — | — | JP | disclosed |