Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.55 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 5/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 4/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 4/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 4/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.41 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.41 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1830567 | 1.00 | KDM4E (0.55) | KDM4EMAPKAPK2LMNACYP1A2CYP3A4 | |
| SCHEMBL14893930 | 0.86 | TNF (0.46) | KDM4EMAPKAPK2LMNACYP1A2CYP3A4 | |
| SCHEMBL14893767 | 0.86 | TNF (0.46) | KDM4EMAPKAPK2LMNACYP1A2CYP3A4 | |
| SCHEMBL14896388 | 0.86 | TNF (0.46) | KDM4EMAPKAPK2LMNACYP1A2CYP3A4 | |
| SCHEMBL2607319 | 0.85 | LMNA (0.53) | KDM4EMAPKAPK2LMNACYP1A2CYP3A4 | |
| SCHEMBL24493538 | 0.82 | LMNA (0.50) | KDM4EMAPKAPK2LMNACYP1A2CYP3A4 | |
| SCHEMBL7231935 | 0.82 | LMNA (0.50) | KDM4EMAPKAPK2LMNACYP1A2CYP3A4 | |
| SCHEMBL22216993 | 0.82 | LMNA (0.50) | KDM4EMAPKAPK2LMNACYP1A2CYP3A4 | |
| SCHEMBL30239333 | 0.82 | CYP3A4 (0.55) | KDM4EMAPKAPK2LMNACYP1A2CYP3A4 | |
| SCHEMBL28462007 | 0.82 | CYP3A4 (0.55) | KDM4EMAPKAPK2LMNACYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118878514-A | Heterocyclic compounds for modulating NR2F6 | TES制药有限责任公司 | 2024-11-01 | — | — | CN | disclosed |
| WO-2023064493-A1 | COMPOUNDS AND METHODS FOR TREATING CORONAVIRUSES | Clear Creek Bio, Inc. (US) | 2023-04-20 | — | — | WO | disclosed |
| CN-115427394-A | Heterocyclic compounds for modulating NR2F6 | TES制药有限责任公司 | 2022-12-02 | — | — | CN | disclosed |