SCHEMBL30098564

SCHEMBL30098564

NC(=O)c1cc2cc3ccccc3cc2cc1O

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.59
GAA P10253 2/20 0.59
MEN1 O00255 2/20 0.59
KMT2A Q03164 2/20 0.59
MITF O75030 1/20 0.59
NCOA1 Q15788 1/20 0.59
TDP1 Q9NUW8 1/20 0.59
NCOA3 Q9Y6Q9 1/20 0.59
KDM4E B2RXH2 3/20 0.56
ALDH1A1 P00352 3/20 0.56
PLAU P00749 3/20 0.54
F2 P00734 2/20 0.54
F10 P00742 2/20 0.54
PLG P00747 2/20 0.54
PLAT P00750 1/20 0.54
HPGD P15428 1/20 0.52
TSHR P16473 1/20 0.52
HSD17B10 Q99714 1/20 0.52
LCK P06239 2/20 0.50
IRAK4 Q9NWZ3 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9127062 1.00 MAPT (0.59) MAPTGAAMEN1KMT2AMITF
SCHEMBL550901 0.96 MAPT (0.63) MAPTGAAMEN1KMT2AMITF
SCHEMBL29374999 0.96 MAPT (0.63) MAPTGAAMEN1KMT2AMITF
SCHEMBL9241086 0.83 BCAT2 (0.49) MAPTGAAMEN1KMT2AMITF
SCHEMBL28439067 0.83 MEN1 (0.50) MAPTGAAMEN1KMT2AMITF
SCHEMBL1004596 0.83 KDM4E (0.63) MAPTGAAMEN1KMT2AMITF
SCHEMBL12953085 0.82 SRC (0.54) MAPTGAAMEN1KMT2AMITF
SCHEMBL2349014 0.82 GRIN2D (0.61) MAPTGAAMEN1KMT2AMITF
SCHEMBL5694817 0.81 LCK (0.79) MAPTGAAMEN1KMT2AMITF
SCHEMBL7404678 0.81 KDM4E (0.61) MAPTGAAMEN1KMT2AMITF

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2657304-B1 AZO DYE, OCULAR LENS MATERIAL, METHOD FOR PRODUCING OCULAR LENS MATERIAL, AND OCULAR LENS MENICON CO LTD (JP) 2022-12-07 EP disclosed