⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL288016 | 0.81 | — | — | |
| SCHEMBL29376210 | 0.81 | — | — | |
| SCHEMBL30960160 | 0.76 | HTR2C (0.37) | — | |
| SCHEMBL38950 | 0.73 | NNMT (0.44) | — | |
| SCHEMBL29416448 | 0.73 | NNMT (0.44) | — | |
| SCHEMBL2608519 | 0.72 | TSHR (0.41) | — | |
| SCHEMBL30903257 | 0.72 | TSHR (0.41) | — | |
| Hydrochloric Acid SCHEMBL21777851 | 0.72 | NNMT (0.42) | — | |
| Hydrochloric Acid SCHEMBL31063054 | 0.72 | NNMT (0.42) | — | |
| SCHEMBL6001078 | 0.72 | PDPK1 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12612424-B2 | HPK1 inhibitors and uses thereof | REGOR PHARMACEUTICALS, INC. (US) | 2026-04-28 | — | — | US | disclosed |
| US-20220389037-A1 | HPK1 INHIBITORS AND USES THEREOF | REGOR PHARMACEUTICALS, INC. | 2022-12-08 | — | — | US | disclosed |