SCHEMBL30099136

SCHEMBL30099136

FC(F)(F)c1cc2ccccc2s1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 4/20 0.45
ASIC3 Q9UHC3 1/20 0.45
LOXL2 Q9Y4K0 1/20 0.45
MGLL Q99685 1/20 0.45
BCL2L1 Q07817 1/20 0.44
CA2 P00918 2/20 0.42
APP P05067 2/20 0.41
AGXT P21549 1/20 0.41
ADRB2 P07550 1/20 0.41
HDAC3 O15379 1/20 0.41
HDAC4 P56524 1/20 0.41
HDAC1 Q13547 1/20 0.41
HDAC7 Q8WUI4 1/20 0.41
HDAC2 Q92769 1/20 0.41
HDAC10 Q969S8 1/20 0.41
HDAC11 Q96DB2 1/20 0.41
HDAC8 Q9BY41 1/20 0.41
HDAC6 Q9UBN7 1/20 0.41
HDAC9 Q9UKV0 1/20 0.41
HDAC5 Q9UQL6 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1765981 1.00 CYP2A6 (0.45) CYP2A6ASIC3LOXL2MGLLBCL2L1
SCHEMBL28129831 0.94 CYP2A6 (0.41) CYP2A6ASIC3LOXL2MGLLBCL2L1
SCHEMBL8543672 0.77 CYP2A6 (0.50) CYP2A6ASIC3LOXL2MGLLBCL2L1
SCHEMBL820486 0.77 MGLL (0.50) CYP2A6ASIC3LOXL2MGLLBCL2L1
SCHEMBL5720315 0.77 CYP2A6 (0.45) CYP2A6ASIC3LOXL2MGLLBCL2L1
SCHEMBL3624705 0.77 BCL2L1 (0.53) CYP2A6ASIC3LOXL2MGLLBCL2L1
SCHEMBL354292 0.76 CYP2A6 (0.48) CYP2A6ASIC3LOXL2MGLLBCL2L1
SCHEMBL18791162 0.75 HDAC3 (0.45) CYP2A6APPHDAC3HDAC4HDAC1
SCHEMBL2387733 0.75 CYP2A6 (0.44) CYP2A6ASIC3LOXL2MGLLBCL2L1
SCHEMBL16686410 0.75 HSP90AA1 (0.40) CYP2A6APP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4087841-A1 PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS Syngenta Crop Protection AG (CH) 2022-11-16 EP disclosed