Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ULK1 | O75385 | 4/20 | 1.00 |
| ▸ | PDK1 | Q15118 | 1/20 | 1.00 |
| ▸ | ULK2 | Q8IYT8 | 1/20 | 1.00 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.54 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.51 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.51 |
| ▸ | SRC | P12931 | 4/20 | 0.51 |
| ▸ | GSK3B | P49841 | 4/20 | 0.51 |
| ▸ | AURKA | O14965 | 1/20 | 0.51 |
| ▸ | PAK4 | O96013 | 1/20 | 0.49 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.49 |
| ▸ | IGF1R | P08069 | 1/20 | 0.48 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.47 |
| ▸ | CDK2 | P24941 | 2/20 | 0.47 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.47 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.46 |
| ▸ | FLT3 | P36888 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31471753 | 0.89 | ULK1 (0.80) | ULK1PDK1ULK2NTRK1NTRK3 | |
| SCHEMBL12430671 | 0.83 | ULK1 (0.72) | ULK1PDK1ULK2NTRK1NTRK3 | |
| SCHEMBL31471758 | 0.83 | ULK1 (0.72) | ULK1PDK1ULK2NTRK1NTRK3 | |
| SCHEMBL13054459 | 0.83 | ULK1 (0.71) | ULK1PDK1ULK2NTRK1NTRK3 | |
| SCHEMBL19654491 | 0.83 | ULK1 (0.71) | ULK1PDK1ULK2NTRK1IGF1R | |
| SCHEMBL12430667 | 0.81 | ULK1 (0.86) | ULK1PDK1ULK2NTRK1NTRK3 | |
| SCHEMBL31471779 | 0.81 | ULK1 (0.86) | ULK1PDK1ULK2NTRK1NTRK3 | |
| SCHEMBL13054460 | 0.81 | ULK1 (0.69) | ULK1PDK1ULK2NTRK1NTRK3 | |
| SCHEMBL31471741 | 0.81 | ULK1 (0.80) | ULK1PDK1ULK2NTRK1NTRK3 | |
| SCHEMBL31471744 | 0.81 | ULK1 (0.80) | ULK1PDK1ULK2NTRK1NTRK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220387569-A1 | INDUCED PLURIPOTENT STEM CELL-BASED CANCER VACCINES | KHLORIS BIOSCIENCES, INC. (US) | 2022-12-08 | — | — | US | disclosed |