Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | KDM5A | P29375 | 3/20 | 0.41 |
| ▸ | PHF8 | Q9UPP1 | 2/20 | 0.41 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 9/20 | 0.41 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29141061 | 0.88 | ADRA1A (0.44) | ADRA1APRMT1HPGDSMN1; SMN2LMNA | |
| SCHEMBL30100538 | 0.85 | HPGD (0.47) | HPGDSMN1; SMN2LMNANPSR1KDM5A | |
| SCHEMBL30100510 | 0.82 | HPGD (0.44) | HPGDSMN1; SMN2LMNANPSR1KDM5A | |
| SCHEMBL30100493 | 0.75 | CNR1 (0.48) | EPHX2 | |
| SCHEMBL32660066 | 0.71 | TSHR (0.63) | LMNAKDM5APHF8KDM4C | |
| SCHEMBL25817168 | 0.70 | HPGD (0.47) | HPGDSMN1; SMN2LMNANPSR1EPHX2 | |
| SCHEMBL25355918 | 0.70 | SPHK1 (0.43) | HPGDSMN1; SMN2LMNANPSR1KDM5A | |
| SCHEMBL8660098 | 0.69 | KDM4C (0.53) | LMNAKDM5APHF8KDM4C | |
| Dodecanoate SCHEMBL21827672 | 0.69 | EPHX2 (0.62) | KDM5APHF8KDM4CEPHX2PLA2G2A | |
| SCHEMBL25816682 | 0.68 | HPGD (0.44) | HPGDSMN1; SMN2LMNANPSR1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4373804-A1 | CYCLOHEXANE LIPIDOIDS FOR NUCLEIC ACID TRANSFECTION AND USE THEREOF | Ustav Organicke Chemie a Biochemie AV CR v.v.i. (CZ) | 2024-05-29 | — | — | EP | disclosed |
| WO-2023001323-A1 | CYCLOHEXANE LIPIDOIDS FOR NUCLEIC ACID TRANSFECTION AND USE THEREOF | Ustav Organicke Chemie A Biochemie AV CR v.v.i. (CZ) | 2023-01-26 | — | — | WO | disclosed |