Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | F2 | P00734 | 2/20 | 0.48 |
| ▸ | F10 | P00742 | 2/20 | 0.48 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.48 |
| ▸ | F7 | P08709 | 2/20 | 0.48 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.48 |
| ▸ | F3 | P13726 | 1/20 | 0.48 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6367148 | 0.94 | HPGD (0.54) | LMNAKDM4EF2F10PRSS1 | |
| SCHEMBL30100613 | 0.91 | KDM4E (0.45) | LMNAKDM4EF2F10PRSS1 | |
| SCHEMBL30100618 | 0.89 | SMPD1 (0.48) | LMNAKDM4EF2F10PRSS1 | |
| SCHEMBL27085659 | 0.86 | KDM4E (0.48) | LMNAKDM4EF2F10PRSS1 | |
| SCHEMBL30100605 | 0.86 | KDM4E (0.44) | LMNAKDM4EF2F10PRSS1 | |
| SCHEMBL6246976 | 0.81 | HPGD (0.55) | KDM4EF2F10PRSS1F7 | |
| SCHEMBL31161055 | 0.80 | LMNA (0.47) | LMNAKDM4EF2F10PRSS1 | |
| SCHEMBL18857785 | 0.80 | LMNA (0.50) | LMNAKDM4EF2F10PRSS1 | |
| Oxalic Acid SCHEMBL10364707 | 0.78 | KDM4E (0.48) | LMNAKDM4EF2F10PRSS1 | |
| SCHEMBL6372129 | 0.78 | CA12 (0.49) | LMNAALDH1A1SMN1; SMN2POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110099893-B | Preparation method of droxidopa and intermediate thereof | 广东东阳光药业有限公司 | 2022-09-27 | — | — | CN | disclosed |