Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.61 |
| ▸ | NPC1 | O15118 | 4/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.61 |
| ▸ | MEN1 | O00255 | 5/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.43 |
| ▸ | NPY1R | P25929 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30100801 | 0.83 | MAPT (0.65) | MAPTNPC1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL701847 | 0.78 | MEN1 (0.60) | MAPTNPC1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL30100844 | 0.76 | MAPT (1.00) | MAPTNPC1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL30100795 | 0.73 | TSHR (0.66) | MAPTNPC1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL28921516 | 0.73 | TSHR (0.66) | MAPTNPC1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL30100808 | 0.73 | MAPT (0.65) | MAPTNPC1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL16688489 | 0.72 | KMT2A (0.79) | MAPTNPC1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL10439864 | 0.72 | MAPT (0.64) | MAPTNPC1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL10385403 | 0.69 | ALOX15 (0.55) | MAPTNPC1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL15046894 | 0.67 | KDM4E (0.50) | MAPTNPC1MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115536646-A | Nematicidal active compound and preparation method and application thereof | 华东理工大学 | 2022-12-30 | — | — | CN | disclosed |