SCHEMBL30100865

SCHEMBL30100865

CN1CCCc2c(Br)cccc21

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TNKS O95271 3/20 0.46
PARP1 P09874 3/20 0.46
TNKS2 Q9H2K2 3/20 0.46
DRD2 P14416 1/20 0.39
CARM1 Q86X55 1/20 0.39
ALDH1A1 P00352 3/20 0.37
GAA P10253 2/20 0.37
MAPT P10636 2/20 0.37
HPGD P15428 2/20 0.37
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
UCHL1 P09936 1/20 0.35
CNR1 P21554 1/20 0.35
CNR2 P34972 1/20 0.35
INMT O95050 1/20 0.34
BRD4 O60885 1/20 0.34
BRD2 P25440 1/20 0.34
KDM4E B2RXH2 1/20 0.34
NOTUM Q6P988 1/20 0.34
HRH3 Q9Y5N1 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28466766 1.00 TNKS (0.46) TNKSPARP1TNKS2DRD2CARM1
SCHEMBL13462411 0.88 S1PR1 (0.37) TNKSPARP1TNKS2CARM1ALDH1A1
SCHEMBL8276444 0.82 NOTUM (0.50) TNKSPARP1TNKS2DRD2ALDH1A1
SCHEMBL26630604 0.79 TNKS (0.43) TNKSPARP1TNKS2DRD2ALDH1A1
SCHEMBL2625794 0.79 NOTUM (0.50) TNKSPARP1TNKS2DRD2ALDH1A1
SCHEMBL23601176 0.79 NOTUM (0.50) TNKSPARP1TNKS2DRD2ALDH1A1
SCHEMBL6402604 0.79 TNKS (0.43) TNKSPARP1TNKS2DRD2ALDH1A1
SCHEMBL13911374 0.79 BCL2L1 (0.46) TNKSPARP1TNKS2DRD2CNR1
SCHEMBL19957595 0.79 TNKS (0.43) TNKSPARP1TNKS2DRD2ALDH1A1
SCHEMBL16019534 0.77 TNKS (0.41) TNKSPARP1TNKS2DRD2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022241418-A1 PHOSPHINATE ESTER-CONTAINING DYES HAVING TUNABLE PROPERTIES AND METHODS OF MAKING THE SAME UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) 2022-11-17 WO disclosed