SCHEMBL6402604

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2484100	0.89	ADRA2C (0.44)	ADRA2CKEAP1SLC6A2SLC6A4SLC6A3
	SCHEMBL8276444	0.81	NOTUM (0.50)	TNKSPARP1TNKS2DRD2SLC6A2
	SCHEMBL28466766	0.79	TNKS (0.46)	TNKSPARP1TNKS2DRD2GAA
	SCHEMBL30100865	0.79	TNKS (0.46)	TNKSPARP1TNKS2DRD2GAA
	SCHEMBL23601176	0.78	NOTUM (0.50)	TNKSPARP1TNKS2DRD2GAA
	SCHEMBL19957595	0.78	TNKS (0.43)	TNKSPARP1TNKS2DRD2GAA
	SCHEMBL23346738	0.78	KEAP1 (0.40)	PARP1ADRA2CKEAP1SLC6A2SLC6A4
	SCHEMBL2625794	0.78	NOTUM (0.50)	TNKSPARP1TNKS2ADRA2CDRD2
	SCHEMBL13911374	0.78	BCL2L1 (0.46)	TNKSPARP1TNKS2DRD2CNR1
	SCHEMBL26630604	0.78	TNKS (0.43)	TNKSPARP1TNKS2DRD2GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.