Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.36 |
| ▸ | DRD3 | P35462 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.34 |
| ▸ | HTR2A | P28223 | 3/20 | 0.34 |
| ▸ | HTR2B | P41595 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | HTR3A | P46098 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30100949 | 0.85 | DRD2 (0.35) | DRD2DRD3SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL7010502 | 0.79 | DRD2 (0.47) | DRD2DRD3HTR2AHTR1A | |
| SCHEMBL30100968 | 0.74 | SLC6A2 (0.33) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL30100971 | 0.74 | SLC6A2 (0.33) | SLC6A2SLC6A4SLC6A3 | |
| Acetone SCHEMBL22660844 | 0.72 | DRD2 (0.44) | DRD2DRD3SLC6A3KCNH2 | |
| SCHEMBL6910639 | 0.70 | DRD3 (0.41) | DRD3KDM4ETSHRHTTSLC6A2 | |
| SCHEMBL8663605 | 0.69 | KDM4E (0.44) | DRD3KDM4ETSHRHTTSLC6A2 | |
| SCHEMBL30100984 | 0.69 | KDM4E (0.36) | DRD2DRD3KDM4ETSHRHTT | |
| SCHEMBL16463813 | 0.69 | SLC6A2 (0.43) | KDM4ETSHRHTTSLC6A2SLC6A4 | |
| SCHEMBL16463814 | 0.69 | SLC6A2 (0.43) | KDM4ETSHRHTTSLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115433205-A | Polycyclic derivative receptor agonist, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2022-12-06 | — | — | CN | disclosed |