Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.78 |
| ▸ | MAPT | P10636 | 3/20 | 0.78 |
| ▸ | TP53 | P04637 | 1/20 | 0.78 |
| ▸ | SCD | O00767 | 14/20 | 0.76 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.62 |
| ▸ | NPC1 | O15118 | 4/20 | 0.61 |
| ▸ | RAB9A | P51151 | 4/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | PKM | P14618 | 1/20 | 0.59 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2481628 | 0.89 | SMN1; SMN2 (0.74) | SMN1; SMN2MAPTTP53SCDLRRK2 | |
| SCHEMBL2514126 | 0.88 | MAPT (0.70) | SMN1; SMN2MAPTTP53SCDLRRK2 | |
| SCHEMBL2247099 | 0.87 | MAPT (1.00) | SMN1; SMN2MAPTTP53SCDLRRK2 | |
| SCHEMBL16553951 | 0.86 | SCD (1.00) | SMN1; SMN2MAPTTP53SCDLRRK2 | |
| SCHEMBL16554316 | 0.85 | SCD (0.80) | SMN1; SMN2MAPTTP53SCDLRRK2 | |
| SCHEMBL16554057 | 0.85 | SCD (0.80) | SMN1; SMN2MAPTTP53SCDLRRK2 | |
| SCHEMBL1987631 | 0.84 | MMP2 (0.65) | SMN1; SMN2MAPTTP53SCDNPC1 | |
| SCHEMBL4912951 | 0.83 | SCD (1.00) | SMN1; SMN2MAPTTP53SCDNPC1 | |
| SCHEMBL2481641 | 0.82 | SCD (0.76) | SMN1; SMN2MAPTTP53SCDLRRK2 | |
| SCHEMBL2482989 | 0.82 | SCD (0.72) | SMN1; SMN2MAPTTP53SCDLRRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115109011-A | Benzothiazole compound, preparation method and application | 河北师范大学 | 2022-09-27 | — | — | CN | disclosed |