Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PCSK9 | Q8NBP7 | 3/20 | 0.75 |
| ▸ | CASP3 | P42574 | 9/20 | 0.65 |
| ▸ | SENP8 | Q96LD8 | 9/20 | 0.65 |
| ▸ | SENP7 | Q9BQF6 | 9/20 | 0.65 |
| ▸ | SENP6 | Q9GZR1 | 9/20 | 0.65 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.55 |
| ▸ | DHODH | Q02127 | 1/20 | 0.53 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.52 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.51 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.51 |
| ▸ | SCD | O00767 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28849839 | 1.00 | PCSK9 (0.75) | PCSK9CASP3SENP8SENP7SENP6 | |
| SCHEMBL28849833 | 0.86 | PCSK9 (1.00) | PCSK9CASP3SENP8SENP7SENP6 | |
| SCHEMBL30101738 | 0.86 | PCSK9 (1.00) | PCSK9CASP3SENP8SENP7SENP6 | |
| SCHEMBL14468043 | 0.85 | MAP3K5 (0.67) | CSNK1DDHODHDYRK1ANPC1RAB9A | |
| SCHEMBL28849881 | 0.82 | CASP3 (0.69) | PCSK9CASP3SENP8SENP7SENP6 | |
| SCHEMBL30101678 | 0.82 | CASP3 (0.69) | PCSK9CASP3SENP8SENP7SENP6 | |
| SCHEMBL30675318 | 0.81 | PCSK9 (1.00) | PCSK9CASP3SENP8SENP7SENP6 | |
| SCHEMBL28849849 | 0.81 | PCSK9 (1.00) | PCSK9CASP3SENP8SENP7SENP6 | |
| SCHEMBL5447236 | 0.81 | DHODH (0.59) | CSNK1DDHODHDYRK1ANPC1RAB9A | |
| SCHEMBL14808404 | 0.80 | DHODH (0.78) | CASP3SENP8SENP7SENP6DHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115109011-B | Benzothiazole compound, preparation method and application | 河北师范大学 | 2023-12-15 | — | — | CN | disclosed |
| CN-115109011-A | Benzothiazole compound, preparation method and application | 河北师范大学 | 2022-09-27 | — | — | CN | disclosed |