Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | AHR | P35869 | 1/20 | 0.38 |
| ▸ | TOP1 | P11387 | 2/20 | 0.38 |
| ▸ | PIM1 | P11309 | 1/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | XBP1 | P17861 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | NTRK1 | P04629 | 3/20 | 0.36 |
| ▸ | TSPO | P30536 | 1/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.35 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.35 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23390259 | 1.00 | EGLN1 (0.40) | EGLN1PTGS1PTGS2AHRTOP1 | |
| SCHEMBL23390257 | 1.00 | EGLN1 (0.40) | EGLN1PTGS1PTGS2AHRTOP1 | |
| SCHEMBL23390113 | 0.92 | PIM1 (0.38) | EGLN1PTGS1PTGS2PIM1CYP11B1 | |
| SCHEMBL29611693 | 0.92 | PIM1 (0.38) | EGLN1PTGS1PTGS2PIM1CYP11B1 | |
| SCHEMBL23390111 | 0.92 | PIM1 (0.38) | EGLN1PTGS1PTGS2PIM1CYP11B1 | |
| SCHEMBL23950645 | 0.92 | EGLN1 (0.39) | EGLN1PTGS1PTGS2AHRTOP1 | |
| SCHEMBL23950999 | 0.91 | PIM1 (0.37) | EGLN1PTGS1PTGS2TOP1PIM1 | |
| SCHEMBL23925586 | 0.91 | EGLN1 (0.39) | EGLN1PTGS1PTGS2AHRTOP1 | |
| SCHEMBL23390306 | 0.91 | CYP2A6 (0.39) | EGLN1PIM1LMNAADORA2AADORA1 | |
| SCHEMBL23390302 | 0.91 | CYP2A6 (0.39) | EGLN1PIM1LMNAADORA2AADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115443276-B | Pyridopyrimidinone derivatives and their use as arene receptor modulators | 东亚ST株式会社 | 2025-04-18 | — | — | CN | claimed |
| CN-115443276-B | Pyridopyrimidinone derivatives and their use as arene receptor modulators | 东亚ST株式会社 | 2025-04-18 | — | — | CN | disclosed |
| CN-115443276-A | Pyridopyrimidinone derivatives and their use as modulators of aromatic hydrocarbon receptors | 东亚ST株式会社 | 2022-12-06 | — | — | CN | disclosed |