Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | XBP1 | P17861 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | PPARD | Q03181 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.42 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23951108 | 1.00 | MAPT (0.45) | MAPTLMNAXBP1SMN1; SMN2NPSR1 | |
| SCHEMBL23951132 | 0.88 | MAPT (0.45) | MAPTLMNAXBP1SMN1; SMN2NPSR1 | |
| SCHEMBL30101970 | 0.82 | DHODH (0.52) | MAPTLMNAXBP1SMN1; SMN2NPSR1 | |
| SCHEMBL23950691 | 0.82 | DHODH (0.52) | MAPTLMNAXBP1SMN1; SMN2NPSR1 | |
| SCHEMBL26294121 | 0.75 | AHR (0.49) | MAPTLMNAXBP1SMN1; SMN2NPSR1 | |
| SCHEMBL26294251 | 0.75 | ACVR1B (0.43) | MAPTTP53POLBTDP1HCRTR1 | |
| SCHEMBL26294134 | 0.72 | AHR (0.63) | MAPTTP53PPARD | |
| SCHEMBL26294114 | 0.72 | AHR (0.63) | MAPTTP53PPARD | |
| SCHEMBL25404965 | 0.71 | AHR (0.52) | MAPTPPARD | |
| SCHEMBL26294510 | 0.71 | CYP2C9 (0.55) | MAPTLMNAXBP1SMN1; SMN2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115443276-B | Pyridopyrimidinone derivatives and their use as arene receptor modulators | 东亚ST株式会社 | 2025-04-18 | — | — | CN | disclosed |
| CN-115443276-A | Pyridopyrimidinone derivatives and their use as modulators of aromatic hydrocarbon receptors | 东亚ST株式会社 | 2022-12-06 | — | — | CN | disclosed |