Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 4/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | XBP1 | P17861 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.46 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.45 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.45 |
| ▸ | KDR | P35968 | 2/20 | 0.43 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23950691 | 1.00 | DHODH (0.52) | DHODHMAPTLMNAXBP1SMN1; SMN2 | |
| SCHEMBL23390311 | 0.87 | DHODH (0.47) | DHODHLMNAKDM4EHTT | |
| SCHEMBL30101958 | 0.82 | MAPT (0.45) | MAPTLMNAXBP1SMN1; SMN2NPSR1 | |
| SCHEMBL23951108 | 0.82 | MAPT (0.45) | MAPTLMNAXBP1SMN1; SMN2NPSR1 | |
| SCHEMBL23951132 | 0.82 | MAPT (0.45) | MAPTLMNAXBP1SMN1; SMN2NPSR1 | |
| SCHEMBL23390607 | 0.79 | KMT2A (0.47) | KMT2ARXFP1 | |
| SCHEMBL28761425 | 0.78 | CHEK1 (0.45) | MAPTTP53POLBKDM4EKDR | |
| SCHEMBL21001306 | 0.78 | KMO (0.50) | DHODHMAPTLMNAXBP1SMN1; SMN2 | |
| SCHEMBL25404965 | 0.77 | AHR (0.52) | DHODHMAPTKDR | |
| SCHEMBL23390095 | 0.76 | CFTR (0.53) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115443276-B | Pyridopyrimidinone derivatives and their use as arene receptor modulators | 东亚ST株式会社 | 2025-04-18 | — | — | CN | disclosed |
| CN-115443276-A | Pyridopyrimidinone derivatives and their use as modulators of aromatic hydrocarbon receptors | 东亚ST株式会社 | 2022-12-06 | — | — | CN | disclosed |