Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 2/20 | 0.51 |
| ▸ | PPARD | Q03181 | 2/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.40 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.37 |
| ▸ | ABL1 | P00519 | 6/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.37 |
| ▸ | DAGLB | Q8NCG7 | 2/20 | 0.37 |
| ▸ | DAGLA | Q9Y4D2 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23390535 | 1.00 | AHR (0.51) | AHRPPARDCYP11B1CYP11B2NPY5R | |
| SCHEMBL23390533 | 1.00 | AHR (0.51) | AHRPPARDCYP11B1CYP11B2NPY5R | |
| SCHEMBL23390134 | 0.91 | AHR (0.41) | AHRPPARDCYP11B1CYP11B2CHRM5 | |
| SCHEMBL23390137 | 0.91 | AHR (0.41) | AHRPPARDCYP11B1CYP11B2CHRM5 | |
| SCHEMBL30101937 | 0.89 | EGLN1 (0.40) | AHRCYP11B1CYP11B2NPY5R | |
| SCHEMBL23390259 | 0.89 | EGLN1 (0.40) | AHRCYP11B1CYP11B2NPY5R | |
| SCHEMBL23390257 | 0.89 | EGLN1 (0.40) | AHRCYP11B1CYP11B2NPY5R | |
| SCHEMBL23390302 | 0.89 | CYP2A6 (0.39) | — | |
| SCHEMBL23390306 | 0.89 | CYP2A6 (0.39) | — | |
| SCHEMBL23390341 | 0.89 | AHR (0.40) | AHRPPARDABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115443276-B | Pyridopyrimidinone derivatives and their use as arene receptor modulators | 东亚ST株式会社 | 2025-04-18 | — | — | CN | claimed |
| CN-115443276-B | Pyridopyrimidinone derivatives and their use as arene receptor modulators | 东亚ST株式会社 | 2025-04-18 | — | — | CN | disclosed |
| CN-115443276-A | Pyridopyrimidinone derivatives and their use as modulators of aromatic hydrocarbon receptors | 东亚ST株式会社 | 2022-12-06 | — | — | CN | disclosed |