SCHEMBL30102083

SCHEMBL30102083

COc1ccc(CNc2ccccn2)cc1

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CXCR4 P61073 1/20 0.74
FABP1 P07148 1/20 0.67
FABP6 P51161 1/20 0.67
KDM4E B2RXH2 1/20 0.64
NPC1 O15118 5/20 0.63
RAB9A P51151 4/20 0.63
GAA P10253 1/20 0.63
TP53 P04637 1/20 0.63
TSHR P16473 1/20 0.63
L3MBTL1 Q9Y468 1/20 0.62
CLK4 Q9HAZ1 3/20 0.57
NOS1 P29475 1/20 0.56
HRH3 Q9Y5N1 1/20 0.55
POLB P06746 2/20 0.54
KMT2A Q03164 1/20 0.53
DYRK1A Q13627 1/20 0.53
F2 P00734 1/20 0.52
MAPT P10636 1/20 0.52
EGFR P00533 1/20 0.52
NR2F2 P24468 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2312890 1.00 CXCR4 (0.74) CXCR4FABP1FABP6KDM4ENPC1
SCHEMBL28467496 0.95 CXCR4 (0.68) CXCR4FABP1FABP6KDM4ENPC1
SCHEMBL28467578 0.86 CXCR4 (0.59) CXCR4FABP1FABP6KDM4ENPC1
SCHEMBL29351380 0.86 CXCR4 (1.00) CXCR4FABP1FABP6KDM4ENPC1
SCHEMBL589266 0.86 CXCR4 (1.00) CXCR4FABP1FABP6KDM4ENPC1
SCHEMBL2144570 0.84 HIF1A (0.56) CXCR4CLK4DYRK1AF2
SCHEMBL4574655 0.84 CYP1A2 (0.66) CXCR4NPC1RAB9AL3MBTL1POLB
SCHEMBL28471889 0.84 CXCR4 (0.74) CXCR4FABP1FABP6KDM4ENPC1
SCHEMBL19892519 0.83 L3MBTL1 (0.61) CXCR4FABP1FABP6KDM4ENPC1
SCHEMBL28460798 0.83 CXCR4 (0.68) CXCR4FABP1FABP6KDM4ENPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111378141-B Force-induced response supramolecular polymer 厦门天策材料科技有限公司 2023-04-07 CN disclosed
CN-111040204-B Force-induced response dynamic polymer and application thereof 厦门天策材料科技有限公司 2023-01-24 CN disclosed