Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.63 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.43 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.43 |
| ▸ | SMO | Q99835 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11856926 | 0.88 | SMN1; SMN2 (0.73) | RAB9ASMN1; SMN2POLBTP53HTT | |
| SCHEMBL11856919 | 0.83 | SMN1; SMN2 (0.67) | RAB9ASMN1; SMN2CYP2C19CYP3A4CYP2C9 | |
| SCHEMBL2447441 | 0.82 | POLB (0.63) | POLBTP53CYP2C19CYP3A4CYP2C9 | |
| SCHEMBL27807206 | 0.79 | POLB (0.58) | RAB9ASMN1; SMN2POLBTP53CYP2C19 | |
| SCHEMBL11855070 | 0.78 | RAB9A (0.93) | RAB9ASMN1; SMN2CYP2C19CYP3A4CYP2C9 | |
| SCHEMBL30102230 | 0.78 | SMN1; SMN2 (1.00) | RAB9ASMN1; SMN2CYP2C19CYP3A4CYP2C9 | |
| SCHEMBL30102046 | 0.77 | SMN1; SMN2 (0.78) | RAB9ASMN1; SMN2HTTALDH1A1CES2 | |
| SCHEMBL28619078 | 0.75 | RAB9A (0.65) | RAB9ASMN1; SMN2POLBTP53CYP3A4 | |
| SCHEMBL8075339 | 0.75 | POLB (0.68) | RAB9APOLBTP53CYP2C19CYP3A4 | |
| SCHEMBL3080983 | 0.75 | SMN1; SMN2 (0.69) | RAB9ASMN1; SMN2TP53CYP3A4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111978201-B | Synthesis method of N, N' -diaryl benzoyl hydrazine compound | 甘肃农业大学 | 2023-01-03 | — | — | CN | disclosed |