Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 11/20 | 0.52 |
| ▸ | MET | P08581 | 7/20 | 0.52 |
| ▸ | TEK | Q02763 | 7/20 | 0.52 |
| ▸ | AURKB | Q96GD4 | 6/20 | 0.52 |
| ▸ | AURKA | O14965 | 5/20 | 0.52 |
| ▸ | RET | P07949 | 8/20 | 0.47 |
| ▸ | PDGFRB | P09619 | 3/20 | 0.47 |
| ▸ | PDGFRA | P16234 | 3/20 | 0.47 |
| ▸ | ABL1 | P00519 | 2/20 | 0.47 |
| ▸ | KIT | P10721 | 2/20 | 0.47 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.47 |
| ▸ | FLT1 | P17948 | 2/20 | 0.47 |
| ▸ | FLT4 | P35916 | 2/20 | 0.47 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.47 |
| ▸ | ERN1 | O75460 | 1/20 | 0.47 |
| ▸ | STK10 | O94804 | 1/20 | 0.47 |
| ▸ | MAP3K6 | O95382 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.47 |
| ▸ | BCR | P11274 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19957060 | 0.92 | KDR (0.62) | KDRMETTEKAURKBAURKA | |
| SCHEMBL19956995 | 0.86 | KDR (0.60) | KDRMETTEKAURKBAURKA | |
| SCHEMBL30102437 | 0.81 | KDR (0.40) | KDRMETTEKAURKBAURKA | |
| SCHEMBL1891385 | 0.78 | PDGFRB (0.64) | KDRPDGFRBPDGFRAFGFR2EGFR | |
| SCHEMBL19957430 | 0.74 | KDR (0.74) | KDRMETTEKAURKBAURKA | |
| SCHEMBL23128557 | 0.73 | KDR (0.60) | KDRMETTEKAURKBAURKA | |
| SCHEMBL1890626 | 0.71 | KDR (0.70) | KDRMETTEKAURKBAURKA | |
| SCHEMBL29186593 | 0.71 | KDR (0.69) | KDRMETTEKAURKBAURKA | |
| SCHEMBL19957106 | 0.70 | KDR (0.59) | KDRMETTEKAURKBAURKA | |
| SCHEMBL19957147 | 0.70 | KDR (0.52) | KDRMETTEKAURKBAURKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112384506-B | Indoline-1-formamide compound, preparation method and application thereof in medicine and pharmacology | 北京诺诚健华医药科技有限公司 | 2023-01-24 | — | — | CN | disclosed |