Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 9/20 | 0.40 |
| ▸ | AURKB | Q96GD4 | 7/20 | 0.40 |
| ▸ | AURKA | O14965 | 6/20 | 0.40 |
| ▸ | MET | P08581 | 6/20 | 0.40 |
| ▸ | TEK | Q02763 | 6/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.37 |
| ▸ | ABL1 | P00519 | 2/20 | 0.36 |
| ▸ | LCK | P06239 | 1/20 | 0.36 |
| ▸ | LYN | P07948 | 1/20 | 0.36 |
| ▸ | IRAK4 | Q9NWZ3 | 8/20 | 0.35 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.34 |
| ▸ | ERN1 | O75460 | 1/20 | 0.34 |
| ▸ | STK10 | O94804 | 1/20 | 0.34 |
| ▸ | MAP3K6 | O95382 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30102506 | 0.81 | KDR (0.52) | KDRAURKBAURKAMETTEK | |
| SCHEMBL19957060 | 0.78 | KDR (0.62) | KDRAURKBAURKAMETTEK | |
| SCHEMBL19956995 | 0.73 | KDR (0.60) | KDRAURKBAURKAMETTEK | |
| SCHEMBL30702373 | 0.70 | KDM4E (0.49) | KDRAURKBAURKAMETTEK | |
| SCHEMBL28427722 | 0.68 | GAA (0.45) | KDRAURKBAURKAMETTEK | |
| SCHEMBL6072869 | 0.65 | HRH3 (0.43) | LCKMAPK14 | |
| SCHEMBL1891385 | 0.65 | PDGFRB (0.64) | KDRPDGFRBPDGFRAFGFR2 | |
| SCHEMBL28425290 | 0.65 | TDP1 (0.41) | KDRAURKBAURKAMETTEK | |
| SCHEMBL565913 | 0.64 | DRD2 (0.53) | ALDH1A1TNIK | |
| SCHEMBL30832847 | 0.64 | DRD2 (0.50) | KDM4EALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112384506-B | Indoline-1-formamide compound, preparation method and application thereof in medicine and pharmacology | 北京诺诚健华医药科技有限公司 | 2023-01-24 | — | — | CN | disclosed |