SCHEMBL30102520

SCHEMBL30102520

O=CC(C=O)(C(=O)c1ccccc1)c1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES1 P23141 4/20 0.48
ALDH1A1 P00352 2/20 0.45
TDP1 Q9NUW8 2/20 0.45
MAPK1 P28482 1/20 0.45
CES2 O00748 2/20 0.41
TSHR P16473 2/20 0.41
DAO P14920 1/20 0.41
NAPRT Q6XQN6 1/20 0.41
CA12 O43570 2/20 0.40
CA1 P00915 2/20 0.40
CA9 Q16790 2/20 0.40
HSD17B10 Q99714 2/20 0.40
HDAC3 O15379 1/20 0.40
IDO1 P14902 1/20 0.40
ALOX15 P16050 1/20 0.40
HDAC1 Q13547 1/20 0.40
HDAC7 Q8WUI4 1/20 0.40
HDAC2 Q92769 1/20 0.40
HDAC8 Q9BY41 1/20 0.40
HDAC6 Q9UBN7 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL548166 0.80 CYP1A2 (0.54) ALDH1A1TDP1MAPK1TSHRHDAC3
SCHEMBL11455532 0.79 CES1 (0.44) CES1ALDH1A1TDP1MAPK1CES2
SCHEMBL1508202 0.78 CES1 (0.56) CES1ALDH1A1TDP1CES2TSHR
SCHEMBL15519395 0.78 CES1 (0.56) CES1ALDH1A1TDP1CES2TSHR
SCHEMBL28196035 0.78 CES1 (0.47) CES1ALDH1A1TDP1MAPK1CES2
SCHEMBL2957871 0.78 CES1 (0.47) CES1ALDH1A1TDP1MAPK1CES2
SCHEMBL28196037 0.76 CES1 (0.46) CES1ALDH1A1TDP1MAPK1CES2
SCHEMBL16147056 0.74 CES1 (0.64) CES1ALDH1A1TDP1MAPK1CES2
SCHEMBL19820114 0.73 CES1 (0.66) CES1ALDH1A1TDP1MAPK1CES2
SCHEMBL1666976 0.73 CES1 (0.61) CES1ALDH1A1TDP1CES2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022272090-A1 HYDROGEL COMPOSITION AND METHODS OF USE RVO 2.0, INC, D/B/A OPTICS MEDICAL (US) 2022-12-29 WO claimed